A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech
The 1989 Nobel Prize Laureates in Chemistry Sidney Altman and Thomas Robert Cech made one of the most important discoveries in molecular genetics. Independently of each other, they demonstrated new experimental evidence that RNA molecules can not only transmit information from DNA but, in certain c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2020-10-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Grigorieva_5_20.pdf |
| _version_ | 1797668797122871296 |
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| author | M. V. Grigorieva V. M. Danilova S. V. Komisarenko |
| author_facet | M. V. Grigorieva V. M. Danilova S. V. Komisarenko |
| author_sort | M. V. Grigorieva |
| collection | DOAJ |
| description | The 1989 Nobel Prize Laureates in Chemistry Sidney Altman and Thomas Robert Cech made one of the most important discoveries in molecular genetics. Independently of each other, they demonstrated new experimental evidence that RNA molecules can not only transmit information from DNA but, in certain conditions, have the enzymatic (catalytic) properties too. As it turned out, the functions previously attributed exclusively to protein enzymes can be also performed by RNA called ribozymes. Later, ribozymes became a new tool in genetic engineering, biochemistry, biotechnology and medicine. |
| first_indexed | 2024-03-11T20:34:42Z |
| format | Article |
| id | doaj.art-d05d593dae14459f8632bbfddec0998a |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-11T20:34:42Z |
| publishDate | 2020-10-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-d05d593dae14459f8632bbfddec0998a2023-10-02T07:19:18ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032020-10-0192515516010.15407/ubj92.05.155A new view of RNA: the 1989 discovery by Sidney Altman and Thomas CechM. V. Grigorieva0https://orcid.org/0000-0002-0397-7154V. M. Danilova1S. V. Komisarenko2https://orcid.org/0000-0002-3244-3194Palladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivPalladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivPalladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivThe 1989 Nobel Prize Laureates in Chemistry Sidney Altman and Thomas Robert Cech made one of the most important discoveries in molecular genetics. Independently of each other, they demonstrated new experimental evidence that RNA molecules can not only transmit information from DNA but, in certain conditions, have the enzymatic (catalytic) properties too. As it turned out, the functions previously attributed exclusively to protein enzymes can be also performed by RNA called ribozymes. Later, ribozymes became a new tool in genetic engineering, biochemistry, biotechnology and medicine.http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Grigorieva_5_20.pdfsidney altmanthomas r. cechrna catalytic propertiesribozymessplicingendonucleases |
| spellingShingle | M. V. Grigorieva V. M. Danilova S. V. Komisarenko A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech The Ukrainian Biochemical Journal sidney altman thomas r. cech rna catalytic properties ribozymes splicing endonucleases |
| title | A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech |
| title_full | A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech |
| title_fullStr | A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech |
| title_full_unstemmed | A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech |
| title_short | A new view of RNA: the 1989 discovery by Sidney Altman and Thomas Cech |
| title_sort | new view of rna the 1989 discovery by sidney altman and thomas cech |
| topic | sidney altman thomas r. cech rna catalytic properties ribozymes splicing endonucleases |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2020/11/Grigorieva_5_20.pdf |
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