Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium

Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium

Planar cell polarity (PCP) signaling polarizes cells within the plane of an epithelium. In the airways, planar cell polarity signaling orients the directional beating of motile cilia required for effective mucociliary clearance. The planar cell polarity signaling mechanism is best understood from wo...

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Bibliographic Details
Main Authors:	Koshi Kunimoto, Alexis T. Weiner, Jeffrey D. Axelrod, Eszter K. Vladar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	cilia planar cell polarity (PCP) prickle airway mouse
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.976182/full

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