SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors
Objective Sentinel node lymphoscintigraphy and biopsy is an essential procedure in theranostics of skin tumors.The aim of this study is to determine the role of SPECT/CT in localization of sentinel lymph node of skin tumors. Methods This study retrospectively reviewed the sentinel node lymphoscin...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2023-07-01
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| Series: | Xiehe Yixue Zazhi |
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| Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0170 |
| _version_ | 1797763311323840512 |
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| author | ZHU Shikun ZHANG Shu LUO Yaping |
| author_facet | ZHU Shikun ZHANG Shu LUO Yaping |
| author_sort | ZHU Shikun |
| collection | DOAJ |
| description | Objective Sentinel node lymphoscintigraphy and biopsy is an essential procedure in theranostics of skin tumors.The aim of this study is to determine the role of SPECT/CT in localization of sentinel lymph node of skin tumors. Methods This study retrospectively reviewed the sentinel node lymphoscintigraphy and biopsy data in patients with skin tumors diagnosed in Peking Union Medical College Hospital from April 2019 to February 2023, and analyzed the role of SPECT/CT in sentinel lymphoscintigraphy. Results Thirty-seven patients were retrospectively enrolled.The primary skin tumor included melanoma (32 patients), squamous cell carcinoma (3 patients), and basal cell carcinoma (2 patients).The sentinel nodes localized in inguinal (23 patients), popliteal (2 patients), axilla (8 patients), trochlea (2 patients), and parotid/periauricular regions (2 patients).Sentinel lymph nodes were localized by SPECT/CT in 36 cases (one patient only underwent planar dynamic imaging).SPECT/CT detected multiple focus in the lymphatic drainage in 16 patients, and in 13 patients they were confirmed to be local retention of the tracer in the lymphatic duct instead of the sentinel lymph node, suggesting false positive uptake.Thirty-four patients underwent sentinel node biopsy 1-4 h after localization, and localization of the sentinel node was consistent with preoperative sentinel node lymphoscintigraphy.Sentinel node biopsy found nodal metastasis in 6 patients (all of them had melanoma in the foot or lower limb). Conclusions Sentinel node lymphoscintigraphy is an important step for localization before sentinel node biopsy.SPECT/CT can help improve the accuracy of localizing sentinel lymph node. |
| first_indexed | 2024-03-12T19:40:45Z |
| format | Article |
| id | doaj.art-d0662ff2e24042d9a6b61f39ddf3c282 |
| institution | Directory Open Access Journal |
| issn | 1674-9081 |
| language | zho |
| last_indexed | 2024-03-12T19:40:45Z |
| publishDate | 2023-07-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj.art-d0662ff2e24042d9a6b61f39ddf3c2822023-08-02T03:54:57ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-07-0114479580110.12290/xhyxzz.2023-0170SPECT/CT in Localization of Sentinel Lymph Node of Skin TumorsZHU ShikunZHANG Shu0LUO YapingDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaObjective Sentinel node lymphoscintigraphy and biopsy is an essential procedure in theranostics of skin tumors.The aim of this study is to determine the role of SPECT/CT in localization of sentinel lymph node of skin tumors. Methods This study retrospectively reviewed the sentinel node lymphoscintigraphy and biopsy data in patients with skin tumors diagnosed in Peking Union Medical College Hospital from April 2019 to February 2023, and analyzed the role of SPECT/CT in sentinel lymphoscintigraphy. Results Thirty-seven patients were retrospectively enrolled.The primary skin tumor included melanoma (32 patients), squamous cell carcinoma (3 patients), and basal cell carcinoma (2 patients).The sentinel nodes localized in inguinal (23 patients), popliteal (2 patients), axilla (8 patients), trochlea (2 patients), and parotid/periauricular regions (2 patients).Sentinel lymph nodes were localized by SPECT/CT in 36 cases (one patient only underwent planar dynamic imaging).SPECT/CT detected multiple focus in the lymphatic drainage in 16 patients, and in 13 patients they were confirmed to be local retention of the tracer in the lymphatic duct instead of the sentinel lymph node, suggesting false positive uptake.Thirty-four patients underwent sentinel node biopsy 1-4 h after localization, and localization of the sentinel node was consistent with preoperative sentinel node lymphoscintigraphy.Sentinel node biopsy found nodal metastasis in 6 patients (all of them had melanoma in the foot or lower limb). Conclusions Sentinel node lymphoscintigraphy is an important step for localization before sentinel node biopsy.SPECT/CT can help improve the accuracy of localizing sentinel lymph node.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0170skin tumorsentinel lymph nodespect/ctdiagnosistreatment |
| spellingShingle | ZHU Shikun ZHANG Shu LUO Yaping SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors Xiehe Yixue Zazhi skin tumor sentinel lymph node spect/ct diagnosis treatment |
| title | SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors |
| title_full | SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors |
| title_fullStr | SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors |
| title_full_unstemmed | SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors |
| title_short | SPECT/CT in Localization of Sentinel Lymph Node of Skin Tumors |
| title_sort | spect ct in localization of sentinel lymph node of skin tumors |
| topic | skin tumor sentinel lymph node spect/ct diagnosis treatment |
| url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0170 |
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