Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone
Summary: Here, we describe a protocol that provides the steps required for the generation of a mouse model of polycystic ovary syndrome (PCOS) by exposing dams to elevated levels of anti-Müllerian hormone during late gestation. This protocol also describes the steps required to assess the PCOS-like...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-09-01
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| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166721003919 |
| _version_ | 1818736641090519040 |
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| author | Nour El Houda Mimouni Paolo Giacobini |
| author_facet | Nour El Houda Mimouni Paolo Giacobini |
| author_sort | Nour El Houda Mimouni |
| collection | DOAJ |
| description | Summary: Here, we describe a protocol that provides the steps required for the generation of a mouse model of polycystic ovary syndrome (PCOS) by exposing dams to elevated levels of anti-Müllerian hormone during late gestation. This protocol also describes the steps required to assess the PCOS-like equivalents of the Rotterdam PCOS diagnostic criteria in mice.For complete details on the use and execution of this protocol, please refer to Tata et al. (2018) and Mimouni et al. (2021). |
| first_indexed | 2024-12-18T00:40:22Z |
| format | Article |
| id | doaj.art-d06de2b5abfa4daca6fa61f8db4ede1e |
| institution | Directory Open Access Journal |
| issn | 2666-1667 |
| language | English |
| last_indexed | 2024-12-18T00:40:22Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | STAR Protocols |
| spelling | doaj.art-d06de2b5abfa4daca6fa61f8db4ede1e2022-12-21T21:26:54ZengElsevierSTAR Protocols2666-16672021-09-0123100684Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormoneNour El Houda Mimouni0Paolo Giacobini1Univ. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Postnatal Brain, Lille Neuroscience & Cognition, UMR-S1172, 59000 Lille, France; Corresponding authorUniv. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Postnatal Brain, Lille Neuroscience & Cognition, UMR-S1172, 59000 Lille, France; Corresponding authorSummary: Here, we describe a protocol that provides the steps required for the generation of a mouse model of polycystic ovary syndrome (PCOS) by exposing dams to elevated levels of anti-Müllerian hormone during late gestation. This protocol also describes the steps required to assess the PCOS-like equivalents of the Rotterdam PCOS diagnostic criteria in mice.For complete details on the use and execution of this protocol, please refer to Tata et al. (2018) and Mimouni et al. (2021).http://www.sciencedirect.com/science/article/pii/S2666166721003919Health SciencesMetabolismModel Organisms |
| spellingShingle | Nour El Houda Mimouni Paolo Giacobini Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone STAR Protocols Health Sciences Metabolism Model Organisms |
| title | Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone |
| title_full | Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone |
| title_fullStr | Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone |
| title_full_unstemmed | Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone |
| title_short | Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone |
| title_sort | polycystic ovary syndrome mouse model by prenatal exposure to high anti mullerian hormone |
| topic | Health Sciences Metabolism Model Organisms |
| url | http://www.sciencedirect.com/science/article/pii/S2666166721003919 |
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