RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells

RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells

Triple-negative breast cancer (TNBC) stands out as the most aggressive subtype within the spectrum of breast cancer. The current clinical guidelines propose treatment strategies involving cytotoxic agents like epirubicin or paclitaxel. However, the emergence of acquired resistance frequently precipi...

Podrobná bibliografie
Hlavní autoři:	Fengxu Lv, Wentao Si, Xiaodan Xu, Xiaogang He, Ying Wang, Yetian Li, Feifei Li
Médium:	Článek
Jazyk:	English
Vydáno:	Elsevier 2024-02-01
Edice:	Neoplasia: An International Journal for Oncology Research
Témata:	Triple negative breast cancer Chemoresistance Cancer stem cells RUNX2 TGF-β
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1476558624000046

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