RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells

Triple-negative breast cancer (TNBC) stands out as the most aggressive subtype within the spectrum of breast cancer. The current clinical guidelines propose treatment strategies involving cytotoxic agents like epirubicin or paclitaxel. However, the emergence of acquired resistance frequently precipi...

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Main Authors: Fengxu Lv, Wentao Si, Xiaodan Xu, Xiaogang He, Ying Wang, Yetian Li, Feifei Li
פורמט: Article
שפה:English
יצא לאור: Elsevier 2024-02-01
סדרה:Neoplasia: An International Journal for Oncology Research
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גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1476558624000046