Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population
Background: Geographical locations and ethnicity may influence variations in normal spleen dimensions, potentially leading to errors in assessment. This study aimed to correlate splenic dimensions with anthropometry and predict their variation with age and body surface area. Materials and Methods...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nobel Medical College Teaching Hospital
2023-12-01
|
| Series: | Journal of Nobel Medical College |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/61472 |
| _version_ | 1797350234329710592 |
|---|---|
| author | Crystal KC Bikash Bikram Adhikari Rakshya Parajuli |
| author_facet | Crystal KC Bikash Bikram Adhikari Rakshya Parajuli |
| author_sort | Crystal KC |
| collection | DOAJ |
| description | Background: Geographical locations and ethnicity may influence variations in normal spleen dimensions, potentially leading to errors in assessment. This study aimed to correlate splenic dimensions with anthropometry and predict their variation with age and body surface area.
Materials and Methods: Subjects (n=384) undergoing abdominal computed tomography were selected by random sampling. Splenic volume was calculated using the standard prolate ellipsoid equation. Correlation of splenic volume with body surface area and body mass index was done with Pearson’s correlation analysis. A multiple regression was run to predict splenic volume from age, height, and body surface area.
Results: The mean age was 45±18 (range, 18-90 years). The mean splenic length, width, thickness, and volume were 7.6 ± 1.7 cm, 8.8 ± 1.5cm, 3.8 ± 0.9 cm, and 139 ± 58.2 cm3, respectively. The splenic width and splenic volume were significantly lower at extremes of age. A significant (P<0.05) correlation was seen between splenic volume, body surface area(r=0.393) and body mass index (r=0.126); a negative correlation was observed between splenic volume and age (r=-0.180). Splenic dimensions were significantly larger in males. Multiple regression revealed that an increase in body surface area (by 10 cm2), predicted increased splenic volume was 4.3 cm3. An increase in age (by 1-year), predicted decrease in splenic volume was 8.3 cm3. For 10 cm increase in height, predicted increase in splenic volume was 1.7cm3.
Conclusion: The study showed a positive correlation between splenic volume and body surface area, as well as body mass index and provides a crucial normative data for assessing splenic enlargement in Nepalese population. |
| first_indexed | 2024-03-08T12:41:45Z |
| format | Article |
| id | doaj.art-d07d9f76a1ca4943be21f53a0e2a3b6f |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-03-08T12:41:45Z |
| publishDate | 2023-12-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-d07d9f76a1ca4943be21f53a0e2a3b6f2024-01-21T09:26:59ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2023-12-011229810210.3126/jonmc.v12i2.6147288593Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese PopulationCrystal KC0Bikash Bikram Adhikari1Rakshya Parajuli2https://orcid.org/0009-0006-8255-4825Department of Radiology, Bir Hospital, Kathmandu, Kathmandu, NepalDepartment of Radiology, Bir Hospital, Kathmandu, Kathmandu, NepalDepartment of Radiology, Bir Hospital, Kathmandu, Kathmandu, NepalBackground: Geographical locations and ethnicity may influence variations in normal spleen dimensions, potentially leading to errors in assessment. This study aimed to correlate splenic dimensions with anthropometry and predict their variation with age and body surface area. Materials and Methods: Subjects (n=384) undergoing abdominal computed tomography were selected by random sampling. Splenic volume was calculated using the standard prolate ellipsoid equation. Correlation of splenic volume with body surface area and body mass index was done with Pearson’s correlation analysis. A multiple regression was run to predict splenic volume from age, height, and body surface area. Results: The mean age was 45±18 (range, 18-90 years). The mean splenic length, width, thickness, and volume were 7.6 ± 1.7 cm, 8.8 ± 1.5cm, 3.8 ± 0.9 cm, and 139 ± 58.2 cm3, respectively. The splenic width and splenic volume were significantly lower at extremes of age. A significant (P<0.05) correlation was seen between splenic volume, body surface area(r=0.393) and body mass index (r=0.126); a negative correlation was observed between splenic volume and age (r=-0.180). Splenic dimensions were significantly larger in males. Multiple regression revealed that an increase in body surface area (by 10 cm2), predicted increased splenic volume was 4.3 cm3. An increase in age (by 1-year), predicted decrease in splenic volume was 8.3 cm3. For 10 cm increase in height, predicted increase in splenic volume was 1.7cm3. Conclusion: The study showed a positive correlation between splenic volume and body surface area, as well as body mass index and provides a crucial normative data for assessing splenic enlargement in Nepalese population.https://www.nepjol.info/index.php/JoNMC/article/view/61472body mass indexbody surface areanepalspleen |
| spellingShingle | Crystal KC Bikash Bikram Adhikari Rakshya Parajuli Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population Journal of Nobel Medical College body mass index body surface area nepal spleen |
| title | Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population |
| title_full | Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population |
| title_fullStr | Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population |
| title_full_unstemmed | Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population |
| title_short | Computed Tomography Assessment of Linear Splenic Dimensions and their Correlation with Anthropometric Measurements in Nepalese Population |
| title_sort | computed tomography assessment of linear splenic dimensions and their correlation with anthropometric measurements in nepalese population |
| topic | body mass index body surface area nepal spleen |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/61472 |
| work_keys_str_mv | AT crystalkc computedtomographyassessmentoflinearsplenicdimensionsandtheircorrelationwithanthropometricmeasurementsinnepalesepopulation AT bikashbikramadhikari computedtomographyassessmentoflinearsplenicdimensionsandtheircorrelationwithanthropometricmeasurementsinnepalesepopulation AT rakshyaparajuli computedtomographyassessmentoflinearsplenicdimensionsandtheircorrelationwithanthropometricmeasurementsinnepalesepopulation |