ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas

ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas

Epithelial-mesenchymal transition (EMT) is a process involved not only in morphogenesis and embryonic development, but also in cancer progression, whereby tumor cells obtain a more aggressive metastatic phenotype. Anterior gradient protein 2 (AGR2) maintains the epithelial phenotype and blocks the i...

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Bibliographic Details
Main Authors: Lucia Sommerova, Eva Ondrouskova, Andrea Martisova, Vassilis Zoumpourlis, Sotirios Galtsidis, Roman Hrstka
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
AGR2
EMT
ZEB1
cancer
Online Access:https://www.mdpi.com/2072-6694/12/6/1614

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