Protective antigenic sites identified in respiratory syncytial virus fusion protein reveals importance of p27 domain

Protective antigenic sites identified in respiratory syncytial virus fusion protein reveals importance of p27 domain

Abstract Respiratory syncytial virus (RSV) vaccines primarily focused on surface fusion (F) protein are under development. Therefore, to identify RSV‐F protective epitopes, we evaluated 14 antigenic sites recognized following primary human RSV infection. BALB/c mice were vaccinated with F peptides,...

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Bibliographic Details
Main Authors: Jeehyun Lee, Youri Lee, Laura Klenow, Elizabeth M Coyle, Juanjie Tang, Supriya Ravichandran, Hana Golding, Surender Khurana
Format: Article
Language:English
Published: Springer Nature 2021-11-01
Series:EMBO Molecular Medicine
Subjects:
epitope
F protein
neutralization
RSV
vaccine
Online Access:https://doi.org/10.15252/emmm.202013847

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