Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in mice

Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in mice

Abstract Background Ovarian follicles, which are the basic units of female reproduction, are composed of oocytes and surrounding somatic (pre) granulosa cells (GCs). A recent study revealed that signaling in somatic preGCs controlled the activation (initial recruitment) of follicles in the adult ova...

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Bibliographic Details
Main Authors: Yanli Dai, Yingnan Bo, Peike Wang, Xueqiang Xu, Meenakshi Singh, Longzhong Jia, Shuo Zhang, Shudong Niu, Kaixin Cheng, Jing Liang, Lu Mu, Kaiying Geng, Guoliang Xia, Chao Wang, Yan Zhang, Hua Zhang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Biology
Subjects:
Embryonic germ cells
Ovarian follicle heterogeneity
Primordial follicle activation
Meiosis
Puberty onset
Online Access:https://doi.org/10.1186/s12915-022-01318-y

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