MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology
Peptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines. On the other hand, they can be used to predict the networks or sites of protein-protein interactions. MimoDB, a new...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-11-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/15/11/8279/ |
| _version_ | 1819038129679499264 |
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| author | Xianlong Wang Hui Ding Hao Lin Feng-Biao Guo Shiyong Li Zhongkui Xia Ping Dai Jian Huang Beibei Ru |
| author_facet | Xianlong Wang Hui Ding Hao Lin Feng-Biao Guo Shiyong Li Zhongkui Xia Ping Dai Jian Huang Beibei Ru |
| author_sort | Xianlong Wang |
| collection | DOAJ |
| description | Peptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines. On the other hand, they can be used to predict the networks or sites of protein-protein interactions. MimoDB, a new repository for these peptides, was developed, in which 10,716 peptides collected from 571 publications were grouped into 1,229 sets. Besides peptide sequences, other important information, such as the target, template, library and complex structure, was also included. MimoDB can be browsed and searched through a user-friendly web interface. For computational biologists, MimoDB can be used to derive customized data sets and benchmarks, which are useful for new algorithm development and tool evaluation. For experimental biologists, their results can be searched against the MimoDB database to exclude possible target-unrelated peptides. The MimoDB database is freely accessible at http://immunet.cn/mimodb/. |
| first_indexed | 2024-12-21T08:32:24Z |
| format | Article |
| id | doaj.art-d084d0211fc04d28a29e95f8758338f5 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-21T08:32:24Z |
| publishDate | 2010-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-d084d0211fc04d28a29e95f8758338f52022-12-21T19:10:10ZengMDPI AGMolecules1420-30492010-11-0115118279828810.3390/molecules15118279MimoDB: a New Repository for Mimotope Data Derived from Phage Display TechnologyXianlong WangHui DingHao LinFeng-Biao GuoShiyong LiZhongkui XiaPing DaiJian HuangBeibei RuPeptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines. On the other hand, they can be used to predict the networks or sites of protein-protein interactions. MimoDB, a new repository for these peptides, was developed, in which 10,716 peptides collected from 571 publications were grouped into 1,229 sets. Besides peptide sequences, other important information, such as the target, template, library and complex structure, was also included. MimoDB can be browsed and searched through a user-friendly web interface. For computational biologists, MimoDB can be used to derive customized data sets and benchmarks, which are useful for new algorithm development and tool evaluation. For experimental biologists, their results can be searched against the MimoDB database to exclude possible target-unrelated peptides. The MimoDB database is freely accessible at http://immunet.cn/mimodb/.http://www.mdpi.com/1420-3049/15/11/8279/mimotopephage displaybiopanningcombinatorial librariestarget-unrelated peptides |
| spellingShingle | Xianlong Wang Hui Ding Hao Lin Feng-Biao Guo Shiyong Li Zhongkui Xia Ping Dai Jian Huang Beibei Ru MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology Molecules mimotope phage display biopanning combinatorial libraries target-unrelated peptides |
| title | MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology |
| title_full | MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology |
| title_fullStr | MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology |
| title_full_unstemmed | MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology |
| title_short | MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology |
| title_sort | mimodb a new repository for mimotope data derived from phage display technology |
| topic | mimotope phage display biopanning combinatorial libraries target-unrelated peptides |
| url | http://www.mdpi.com/1420-3049/15/11/8279/ |
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