Regulation of histone acetylation by garcinol blocks the reconsolidation of heroin-associated memory

Regulation of histone acetylation by garcinol blocks the reconsolidation of heroin-associated memory

Drug-associated long-term memories underlie substance use disorders, including heroin use disorder (HUD), which are difficult to eliminate through existing therapies. Addictive memories may become unstable when reexposed to drug-related cues and need to be stabilized again through protein resynthesi...

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Bibliographic Details
Main Authors: Junzhe Cheng, Binbin Wang, Hongkun Hu, Xinzhu Lin, Yuhang Liu, Jiang Lin, Jinlong Zhang, Shuliang Niu, Jie Yan
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Heroin
Garcinol
Histone acetylation
Reconsolidation
Reinstatement
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002981

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