Apomorphine in the Treatment of Parkinson’s Disease

Apomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson’s disease, which could be administered as an intermittent or continuous infusion. Although apomorphine treatment has been shown to be effective on motor fluctuations and dyskinesias, th...

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Main Author: Serhat Özkan
Format: Article
Language:English
Published: Galenos Yayinevi 2021-12-01
Series:Türk Nöroloji Dergisi
Subjects:
Online Access:https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-06706&look4=
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author Serhat Özkan
author_facet Serhat Özkan
author_sort Serhat Özkan
collection DOAJ
description Apomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson’s disease, which could be administered as an intermittent or continuous infusion. Although apomorphine treatment has been shown to be effective on motor fluctuations and dyskinesias, there is no sufficient consensus regarding the administration of apomorphine test or infusion, and the management of the treatment. In this review, our aim is to create a “treatment management guideline,” which includes recommendations for the use of apomorphine in the clinical practice, and to discuss the problems encountered in both intermittent and continuous infusion applications, in the light of the literature.
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spelling doaj.art-d0872f83027145e2864eb187a18de9ef2023-02-15T16:19:02ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452021-12-0127435836510.4274/tnd.2021.06706Apomorphine in the Treatment of Parkinson’s DiseaseSerhat Özkan0https://orcid.org/0000-0002-5874-5270Eskisehir Osmangazi University Faculty of Medicine, Department of Neurology, Eskisehir, TurkeyApomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson’s disease, which could be administered as an intermittent or continuous infusion. Although apomorphine treatment has been shown to be effective on motor fluctuations and dyskinesias, there is no sufficient consensus regarding the administration of apomorphine test or infusion, and the management of the treatment. In this review, our aim is to create a “treatment management guideline,” which includes recommendations for the use of apomorphine in the clinical practice, and to discuss the problems encountered in both intermittent and continuous infusion applications, in the light of the literature.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-06706&look4=apomorphineparkinson’s diseasetreatment
spellingShingle Serhat Özkan
Apomorphine in the Treatment of Parkinson’s Disease
Türk Nöroloji Dergisi
apomorphine
parkinson’s disease
treatment
title Apomorphine in the Treatment of Parkinson’s Disease
title_full Apomorphine in the Treatment of Parkinson’s Disease
title_fullStr Apomorphine in the Treatment of Parkinson’s Disease
title_full_unstemmed Apomorphine in the Treatment of Parkinson’s Disease
title_short Apomorphine in the Treatment of Parkinson’s Disease
title_sort apomorphine in the treatment of parkinson s disease
topic apomorphine
parkinson’s disease
treatment
url https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-06706&look4=
work_keys_str_mv AT serhatozkan apomorphineinthetreatmentofparkinsonsdisease