High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report

Objective: Undifferentiated pleomorphic sarcoma (UPS) is rare and affects mainly the elderly. Due to the low incidence and heterogeneous variety of this sarcoma, little is known about the UPS regarding clinical behavior, treatment strategies and prognosis. The objective is to describe the case of a...

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Main Authors: D. Frainer, C. Da Silveira Welter, C. Theis, H. Fiamoncini, G: Bachtold, L. A. Seyboth
Format: Article
Language:English
Published: Verduci Editore 2022-03-01
Series:World Cancer Research Journal
Subjects:
Online Access:https://www.wcrj.net/wp-content/uploads/sites/5/2022/03/e2238.pdf
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author D. Frainer
C. Da Silveira Welter
C. Theis
H. Fiamoncini
G: Bachtold
L. A. Seyboth
author_facet D. Frainer
C. Da Silveira Welter
C. Theis
H. Fiamoncini
G: Bachtold
L. A. Seyboth
author_sort D. Frainer
collection DOAJ
description Objective: Undifferentiated pleomorphic sarcoma (UPS) is rare and affects mainly the elderly. Due to the low incidence and heterogeneous variety of this sarcoma, little is known about the UPS regarding clinical behavior, treatment strategies and prognosis. The objective is to describe the case of a young patient, with a UPS measuring 14 × 11.2 × 8.2 cm, with a 6-month evolution and no metastases. Case Report: A female patient, 34 years old, reported the presence of nodulation in the left gluteal region for 6 months with progressive growth associated with pain, weight loss of 10 kg in the last 2 months. An anatomopathological study showed a malignant neoplasm of spindle cells and high-grade pleomorphic sarcoma on immunohistochemistry. Neoadjuvant chemotherapy and complete resection of the lesion with subsequent adjuvant radiotherapy were performed. Results: Since undifferentiated pleomorphic sarcoma has a better prognosis when diagnosed early and in a small size, it is crucial to immediately recognize and assess any enlarged mass and nodule, even though it is a rare diagnosis. Conclusions: Due to the high rate of recurrence and metastasis, monitoring should be carried out regularly for years after surgical excision.
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spelling doaj.art-d08a103cd72f4767aa724df81662a9482022-12-22T04:23:17ZengVerduci EditoreWorld Cancer Research Journal2372-34162022-03-01910.32113/wcrj_20223_22382238High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case reportD. Frainer0C. Da Silveira Welter1C. Theis2H. Fiamoncini3G: Bachtold4L. A. Seyboth5Universidade da Região de Joinville, Medical School, Joinville, BrazilHospital Municipal São José, General Surgery, Joinville, BrazilHospital Municipal São José, General Surgery, Joinville, BrazilUniversidade da Região de Joinville, Medical School, Joinville, BrazilHospital Municipal São José, Plastic Surgery, Joinville, BrazilHospital Municipal São José, Oncology Surgery, Joinville, BrazilObjective: Undifferentiated pleomorphic sarcoma (UPS) is rare and affects mainly the elderly. Due to the low incidence and heterogeneous variety of this sarcoma, little is known about the UPS regarding clinical behavior, treatment strategies and prognosis. The objective is to describe the case of a young patient, with a UPS measuring 14 × 11.2 × 8.2 cm, with a 6-month evolution and no metastases. Case Report: A female patient, 34 years old, reported the presence of nodulation in the left gluteal region for 6 months with progressive growth associated with pain, weight loss of 10 kg in the last 2 months. An anatomopathological study showed a malignant neoplasm of spindle cells and high-grade pleomorphic sarcoma on immunohistochemistry. Neoadjuvant chemotherapy and complete resection of the lesion with subsequent adjuvant radiotherapy were performed. Results: Since undifferentiated pleomorphic sarcoma has a better prognosis when diagnosed early and in a small size, it is crucial to immediately recognize and assess any enlarged mass and nodule, even though it is a rare diagnosis. Conclusions: Due to the high rate of recurrence and metastasis, monitoring should be carried out regularly for years after surgical excision.https://www.wcrj.net/wp-content/uploads/sites/5/2022/03/e2238.pdfpleomorphic sarcomahigh gradecase report
spellingShingle D. Frainer
C. Da Silveira Welter
C. Theis
H. Fiamoncini
G: Bachtold
L. A. Seyboth
High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
World Cancer Research Journal
pleomorphic sarcoma
high grade
case report
title High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
title_full High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
title_fullStr High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
title_full_unstemmed High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
title_short High-grade undifferentiated pleomorphic sarcoma in the gluteus with a v-y flap: a case report
title_sort high grade undifferentiated pleomorphic sarcoma in the gluteus with a v y flap a case report
topic pleomorphic sarcoma
high grade
case report
url https://www.wcrj.net/wp-content/uploads/sites/5/2022/03/e2238.pdf
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AT ctheis highgradeundifferentiatedpleomorphicsarcomainthegluteuswithavyflapacasereport
AT hfiamoncini highgradeundifferentiatedpleomorphicsarcomainthegluteuswithavyflapacasereport
AT gbachtold highgradeundifferentiatedpleomorphicsarcomainthegluteuswithavyflapacasereport
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