Graft-Derived Cell-Free DNA Quantification following Liver Transplantation Using Tissue-Specific DNA Methylation and Donor-Specific Genotyping Techniques: An Orthogonal Comparison Study

Graft-Derived Cell-Free DNA Quantification following Liver Transplantation Using Tissue-Specific DNA Methylation and Donor-Specific Genotyping Techniques: An Orthogonal Comparison Study

<i>Background</i>: Graft-derived cell-free DNA (gdcfDNA) analysis has shown promise as a non-invasive tool for monitoring organ health following solid organ transplantation. A number of gdcfDNA analysis techniques have been described; however, the majority rely on sequencing or prior gen...

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Bibliographic Details
Main Authors: Daniel R. A. Cox, Tess McClure, Fan Zhang, Boris Ka Leong Wong, Adam Testro, Su Kah Goh, Vijayaragavan Muralidharan, Alexander Dobrovic
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Epigenomes
Subjects:
cell-free DNA
cfDNA
DNA methylation
liver Transplant*
donor-derived cfDNA
graft-derived cfDNA
Online Access:https://www.mdpi.com/2075-4655/7/2/11

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