A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation

A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation

Abstract Introduction Papillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like nuclear grooving, nuclear clearing, and intra-nuclear inclusions. However, nuclear grooves are observed even in benign thyroid lesions (BTL) l...

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Bibliographic Details
Main Authors: Basavaraj Rangalakshmi Ashwini, Chandran Nirmala, Muthuvelu Natarajan, Dayananda S Biligi
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Thyroid Research
Subjects:
Benign thyroid lesions
Nuclear grooving
RET/PTC1
And RET/PTC3 gene translocation
Online Access:https://doi.org/10.1186/s13044-023-00161-9

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