Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response

Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response

Parathyroid hormone (PTH) plays critical, but distinct, roles in bone remodeling, including bone formation (anabolic response) and resorption (catabolic response). Although its signaling and function have been extensively investigated, it just began to be understood how distinct functions are induce...

Full description

Bibliographic Details
Main Authors: Lei Xiong, Wen-Fang Xia, Fu-Lei Tang, Jin-Xiu Pan, Lin Mei, Wen-Cheng Xiong
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:EBioMedicine
Subjects:
VPS35
Retromer
PTH1R
PPP1R14C
Osteoblasts
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302122

Similar Items

Similar Items