Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
Abstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between cli...
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Format: | Article |
Language: | English |
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SpringerOpen
2023-07-01
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Series: | The Egyptian Heart Journal |
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Online Access: | https://doi.org/10.1186/s43044-023-00388-9 |
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author | Reza Faramarzzadeh Farin Fekrat Arian Haghtalab |
author_facet | Reza Faramarzzadeh Farin Fekrat Arian Haghtalab |
author_sort | Reza Faramarzzadeh |
collection | DOAJ |
description | Abstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between clinical and laboratory-related risk factors in atherosclerosis patients diagnosed with CSF. Results The research encompassed a study group of 142 individuals, with a mean age of 52.47 ± 10.62, and a male representation of 47.7%. A thorough statistical analysis was conducted, indicating that there were no noteworthy variations in age, gender, smoking history, hematocrit, blood sugar, and HDL levels between the groups of cases and controls (P > 0.05). Subsequent analysis of the data indicated that there were significant differences in history of hypertension, LDL, and BMI measurements between the groups of subjects who were designated as cases and those who were designated as controls. Our study revealed that male gender, a history of hypertension, and BMI were identified as independent predictors of CSF (P < 0.05). Conclusions After modeling regression, we were able to conclude that male gender, BMI, and history of hypertension are reliable predictors of slow coronary flow. These findings add to our growing understanding of the complex interplay between clinical and laboratory risk factors in the development and progression of CSF. |
first_indexed | 2024-03-12T23:22:41Z |
format | Article |
id | doaj.art-d08fdbb0bde74349adb2e3a8dbe1f980 |
institution | Directory Open Access Journal |
issn | 2090-911X |
language | English |
last_indexed | 2024-03-12T23:22:41Z |
publishDate | 2023-07-01 |
publisher | SpringerOpen |
record_format | Article |
series | The Egyptian Heart Journal |
spelling | doaj.art-d08fdbb0bde74349adb2e3a8dbe1f9802023-07-16T11:20:19ZengSpringerOpenThe Egyptian Heart Journal2090-911X2023-07-017511610.1186/s43044-023-00388-9Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysisReza Faramarzzadeh0Farin Fekrat1Arian Haghtalab2Department of Cardiology, Ayatollah Taleghani HospitalDepartment of Cardiology, Ayatollah Taleghani HospitalDepartment of Cardiology, Ayatollah Taleghani HospitalAbstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between clinical and laboratory-related risk factors in atherosclerosis patients diagnosed with CSF. Results The research encompassed a study group of 142 individuals, with a mean age of 52.47 ± 10.62, and a male representation of 47.7%. A thorough statistical analysis was conducted, indicating that there were no noteworthy variations in age, gender, smoking history, hematocrit, blood sugar, and HDL levels between the groups of cases and controls (P > 0.05). Subsequent analysis of the data indicated that there were significant differences in history of hypertension, LDL, and BMI measurements between the groups of subjects who were designated as cases and those who were designated as controls. Our study revealed that male gender, a history of hypertension, and BMI were identified as independent predictors of CSF (P < 0.05). Conclusions After modeling regression, we were able to conclude that male gender, BMI, and history of hypertension are reliable predictors of slow coronary flow. These findings add to our growing understanding of the complex interplay between clinical and laboratory risk factors in the development and progression of CSF.https://doi.org/10.1186/s43044-023-00388-9Risk factorSlow coronary flowCSFCSFPInflammation |
spellingShingle | Reza Faramarzzadeh Farin Fekrat Arian Haghtalab Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis The Egyptian Heart Journal Risk factor Slow coronary flow CSF CSFP Inflammation |
title | Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis |
title_full | Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis |
title_fullStr | Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis |
title_full_unstemmed | Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis |
title_short | Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis |
title_sort | evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow a case control analysis |
topic | Risk factor Slow coronary flow CSF CSFP Inflammation |
url | https://doi.org/10.1186/s43044-023-00388-9 |
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