Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis

Abstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between cli...

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Main Authors: Reza Faramarzzadeh, Farin Fekrat, Arian Haghtalab
Format: Article
Language:English
Published: SpringerOpen 2023-07-01
Series:The Egyptian Heart Journal
Subjects:
Online Access:https://doi.org/10.1186/s43044-023-00388-9
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author Reza Faramarzzadeh
Farin Fekrat
Arian Haghtalab
author_facet Reza Faramarzzadeh
Farin Fekrat
Arian Haghtalab
author_sort Reza Faramarzzadeh
collection DOAJ
description Abstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between clinical and laboratory-related risk factors in atherosclerosis patients diagnosed with CSF. Results The research encompassed a study group of 142 individuals, with a mean age of 52.47 ± 10.62, and a male representation of 47.7%. A thorough statistical analysis was conducted, indicating that there were no noteworthy variations in age, gender, smoking history, hematocrit, blood sugar, and HDL levels between the groups of cases and controls (P > 0.05). Subsequent analysis of the data indicated that there were significant differences in history of hypertension, LDL, and BMI measurements between the groups of subjects who were designated as cases and those who were designated as controls. Our study revealed that male gender, a history of hypertension, and BMI were identified as independent predictors of CSF (P < 0.05). Conclusions After modeling regression, we were able to conclude that male gender, BMI, and history of hypertension are reliable predictors of slow coronary flow. These findings add to our growing understanding of the complex interplay between clinical and laboratory risk factors in the development and progression of CSF.
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spelling doaj.art-d08fdbb0bde74349adb2e3a8dbe1f9802023-07-16T11:20:19ZengSpringerOpenThe Egyptian Heart Journal2090-911X2023-07-017511610.1186/s43044-023-00388-9Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysisReza Faramarzzadeh0Farin Fekrat1Arian Haghtalab2Department of Cardiology, Ayatollah Taleghani HospitalDepartment of Cardiology, Ayatollah Taleghani HospitalDepartment of Cardiology, Ayatollah Taleghani HospitalAbstract Background Coronary slow flow (CSF) is an angiographic entity distinguished by the delayed filling of the epicardial coronary arteries in the lack of significant obstructive artery disease. The pathological causes are still unknown. This study aimed to elucidate the relationship between clinical and laboratory-related risk factors in atherosclerosis patients diagnosed with CSF. Results The research encompassed a study group of 142 individuals, with a mean age of 52.47 ± 10.62, and a male representation of 47.7%. A thorough statistical analysis was conducted, indicating that there were no noteworthy variations in age, gender, smoking history, hematocrit, blood sugar, and HDL levels between the groups of cases and controls (P > 0.05). Subsequent analysis of the data indicated that there were significant differences in history of hypertension, LDL, and BMI measurements between the groups of subjects who were designated as cases and those who were designated as controls. Our study revealed that male gender, a history of hypertension, and BMI were identified as independent predictors of CSF (P < 0.05). Conclusions After modeling regression, we were able to conclude that male gender, BMI, and history of hypertension are reliable predictors of slow coronary flow. These findings add to our growing understanding of the complex interplay between clinical and laboratory risk factors in the development and progression of CSF.https://doi.org/10.1186/s43044-023-00388-9Risk factorSlow coronary flowCSFCSFPInflammation
spellingShingle Reza Faramarzzadeh
Farin Fekrat
Arian Haghtalab
Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
The Egyptian Heart Journal
Risk factor
Slow coronary flow
CSF
CSFP
Inflammation
title Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
title_full Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
title_fullStr Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
title_full_unstemmed Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
title_short Evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow: a case–control analysis
title_sort evaluation of the relationship between clinical and laboratory risk factors in atherosclerosis patients with coronary slow flow a case control analysis
topic Risk factor
Slow coronary flow
CSF
CSFP
Inflammation
url https://doi.org/10.1186/s43044-023-00388-9
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