Deletion of the lipid droplet protein kinase gene affects lipid droplets biogenesis, parasite infectivity, and resistance to trivalent antimony in Leishmania infantum.

Deletion of the lipid droplet protein kinase gene affects lipid droplets biogenesis, parasite infectivity, and resistance to trivalent antimony in Leishmania infantum.

Show other versions (1)

The Lipid Droplet Protein Kinase (LDK) facilitates lipid droplet (LD) biogenesis, organelles involved in various metabolic and signaling functions in trypanosomatids. As LDK's function has not been previously explored in Leishmania spp., we utilized CRISPR/Cas9 technology to generate LDK-knocko...

Full description

Bibliographic Details
Main Authors: Juliana Martins Ribeiro, Paula Alves Silva, Héllida Marina Costa-Silva, Ana Maria Murta Santi, Silvane Maria Fonseca Murta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011880&type=printable

Similar Items

Similar Items