Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency
Microwave (MW) ablation is becoming a routine technology in the interventional radiology field. A new approach combining MW ablation and chemical ablation is developed in this paper. The rationale for the development of this Microwave-Assisted Chemical Ablation (MA-CA) technology was to improve the...
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MDPI AG
2023-06-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/13/12/7177 |
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| author | J. R. Jocelyn Paré Jacqueline M. R. Bélanger Gabriel Cormier Delphine Foucher Antony Thériault Jean-Christophe Savoie Jean-François Rochas |
| author_facet | J. R. Jocelyn Paré Jacqueline M. R. Bélanger Gabriel Cormier Delphine Foucher Antony Thériault Jean-Christophe Savoie Jean-François Rochas |
| author_sort | J. R. Jocelyn Paré |
| collection | DOAJ |
| description | Microwave (MW) ablation is becoming a routine technology in the interventional radiology field. A new approach combining MW ablation and chemical ablation is developed in this paper. The rationale for the development of this Microwave-Assisted Chemical Ablation (MA-CA) technology was to improve the utility of thermal ablation as a minimally invasive treatment for cancer. The experimental conditions for ex vivo bovine liver samples were: A—100 W (120 s) with no addition of ethanol; B—100 W (30 s), wait (60 s) (no power), and 100 W (90 s) with no addition of ethanol; C—100 W (30 s), wait (60 s), 100 W (30 s), and 100 W (60 s) with the addition of 5 mL ethanol; and D—100 W (30 s), wait (60 s), 100 W (30 s), 0 W (30 s) with the addition of 2.5 mL ethanol, and 100 W (60 s) with the addition of 5 mL ethanol (12,000 Joules Total). The results showed that with the use of ethanol, the ablation zone was enlarged and revealed improved sphericity. This novel combination has greater advantages than either technology individually. The objective is to increase the precision and efficiency of MW ablation and to broaden the range of tissues and pathologies that can be treated using this new approach, and to validate the benefits that arise from combining the advantages of MW and chemical ablation in a relevant setting. |
| first_indexed | 2024-03-11T02:49:08Z |
| format | Article |
| id | doaj.art-d090f693c1b047b597dc5a712356ae2d |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-11T02:49:08Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-d090f693c1b047b597dc5a712356ae2d2023-11-18T09:10:17ZengMDPI AGApplied Sciences2076-34172023-06-011312717710.3390/app13127177Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of EfficiencyJ. R. Jocelyn Paré0Jacqueline M. R. Bélanger1Gabriel Cormier2Delphine Foucher3Antony Thériault4Jean-Christophe Savoie5Jean-François Rochas6Atlantic Cancer Research Institute, Dr. Georges-L.-Dumont University Hospital Centre, 35 Providence Street, Moncton, NB E1C 8X3, CanadaAtlantic Cancer Research Institute, Dr. Georges-L.-Dumont University Hospital Centre, 35 Providence Street, Moncton, NB E1C 8X3, CanadaDepartment of Electrical Engineering, Université de Moncton, Moncton, NB E1A 3E9, CanadaDepartment of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, CanadaAtlantic Cancer Research Institute, Dr. Georges-L.-Dumont University Hospital Centre, 35 Providence Street, Moncton, NB E1C 8X3, CanadaAtlantic Cancer Research Institute, Dr. Georges-L.-Dumont University Hospital Centre, 35 Providence Street, Moncton, NB E1C 8X3, CanadaWAVES CONCEPT, 6 Allée Claude Dumont, 69300 Caluire et Cuire, FranceMicrowave (MW) ablation is becoming a routine technology in the interventional radiology field. A new approach combining MW ablation and chemical ablation is developed in this paper. The rationale for the development of this Microwave-Assisted Chemical Ablation (MA-CA) technology was to improve the utility of thermal ablation as a minimally invasive treatment for cancer. The experimental conditions for ex vivo bovine liver samples were: A—100 W (120 s) with no addition of ethanol; B—100 W (30 s), wait (60 s) (no power), and 100 W (90 s) with no addition of ethanol; C—100 W (30 s), wait (60 s), 100 W (30 s), and 100 W (60 s) with the addition of 5 mL ethanol; and D—100 W (30 s), wait (60 s), 100 W (30 s), 0 W (30 s) with the addition of 2.5 mL ethanol, and 100 W (60 s) with the addition of 5 mL ethanol (12,000 Joules Total). The results showed that with the use of ethanol, the ablation zone was enlarged and revealed improved sphericity. This novel combination has greater advantages than either technology individually. The objective is to increase the precision and efficiency of MW ablation and to broaden the range of tissues and pathologies that can be treated using this new approach, and to validate the benefits that arise from combining the advantages of MW and chemical ablation in a relevant setting.https://www.mdpi.com/2076-3417/13/12/7177Microwave-Assisted Ablation (MWA)Microwave-Assisted Chemical Ablation (MA-CA)Microwave-Assisted Processes (MAP<sup>TM</sup>)tissue ablationsusceptors |
| spellingShingle | J. R. Jocelyn Paré Jacqueline M. R. Bélanger Gabriel Cormier Delphine Foucher Antony Thériault Jean-Christophe Savoie Jean-François Rochas Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency Applied Sciences Microwave-Assisted Ablation (MWA) Microwave-Assisted Chemical Ablation (MA-CA) Microwave-Assisted Processes (MAP<sup>TM</sup>) tissue ablation susceptors |
| title | Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency |
| title_full | Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency |
| title_fullStr | Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency |
| title_full_unstemmed | Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency |
| title_short | Microwave-Assisted Chemical Ablation (MA-CA): A Novel Microwave-Assisted Tissue Ablation Procedure—Preliminary Assessment of Efficiency |
| title_sort | microwave assisted chemical ablation ma ca a novel microwave assisted tissue ablation procedure preliminary assessment of efficiency |
| topic | Microwave-Assisted Ablation (MWA) Microwave-Assisted Chemical Ablation (MA-CA) Microwave-Assisted Processes (MAP<sup>TM</sup>) tissue ablation susceptors |
| url | https://www.mdpi.com/2076-3417/13/12/7177 |
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