CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury.

CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury.

<h4>Background</h4>Chronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly multifunctional glycoprotein C...

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Main Authors: Christine Yee, Nathan M Main, Alexandra Terry, Igor Stevanovski, Annette Maczurek, Alison J Morgan, Sarah Calabro, Alison J Potter, Tina L Iemma, David G Bowen, Golo Ahlenstiel, Fiona J Warner, Geoffrey W McCaughan, Susan V McLennan, Nicholas A Shackel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215557

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