The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients
Abstract Objective Triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is correlated with metabolic diseases. The prevalence of sarcopenia is significantly higher in type 2 diabetes mellitus (T2DM) patients compared with healthy controls. The purpose of our study is to evaluate the co...
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Endocrine Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12902-023-01349-8 |
| _version_ | 1797836442335969280 |
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| author | Qingsong Fu Zhenwen Zhang Wenchao Hu Yinrong Yang |
| author_facet | Qingsong Fu Zhenwen Zhang Wenchao Hu Yinrong Yang |
| author_sort | Qingsong Fu |
| collection | DOAJ |
| description | Abstract Objective Triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is correlated with metabolic diseases. The prevalence of sarcopenia is significantly higher in type 2 diabetes mellitus (T2DM) patients compared with healthy controls. The purpose of our study is to evaluate the correlation of TG/HDL-C ratio with muscle mass in T2DM patients. Method Our study consists of 1048 T2DM inpatients recruited from the department of endocrinology. Skeletal muscle index (SMI) was detected with a dual energy X-ray absorptiometry method. Low muscle mass was diagnosed using the criteria of SMI less than 7.0 kg/m2 (in male subjects) or 5.4 kg/m2 (in female subjects). Result The prevalence of low muscle mass was 20.9% and 14.5% in male and female groups respectively. SMI was correlated with TG/HDL ratio after adjustment for age, duration of diabetes, diastolic blood pressure (DBP), and HbA1c in male subgroup. In female subgroup, SMI was associated with TG/HDL ratio after adjustment for age and DBP. Conclusion Higher TG/HDL-C ratio is correlated with muscle mass in T2DM patients. |
| first_indexed | 2024-04-09T15:08:59Z |
| format | Article |
| id | doaj.art-d098aba4b17d49ac94b2eb1f9e76fcc8 |
| institution | Directory Open Access Journal |
| issn | 1472-6823 |
| language | English |
| last_indexed | 2024-04-09T15:08:59Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj.art-d098aba4b17d49ac94b2eb1f9e76fcc82023-04-30T11:18:43ZengBMCBMC Endocrine Disorders1472-68232023-04-012311510.1186/s12902-023-01349-8The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patientsQingsong Fu0Zhenwen Zhang1Wenchao Hu2Yinrong Yang3Department of Central Laboratory and Mitochondrial Medicine Laboratory, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong UniversityDepartment of Cadre Health Care, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong UniversityDepartment of Endocrinology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong UniversityDepartment of Laboratory, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong UniversityAbstract Objective Triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is correlated with metabolic diseases. The prevalence of sarcopenia is significantly higher in type 2 diabetes mellitus (T2DM) patients compared with healthy controls. The purpose of our study is to evaluate the correlation of TG/HDL-C ratio with muscle mass in T2DM patients. Method Our study consists of 1048 T2DM inpatients recruited from the department of endocrinology. Skeletal muscle index (SMI) was detected with a dual energy X-ray absorptiometry method. Low muscle mass was diagnosed using the criteria of SMI less than 7.0 kg/m2 (in male subjects) or 5.4 kg/m2 (in female subjects). Result The prevalence of low muscle mass was 20.9% and 14.5% in male and female groups respectively. SMI was correlated with TG/HDL ratio after adjustment for age, duration of diabetes, diastolic blood pressure (DBP), and HbA1c in male subgroup. In female subgroup, SMI was associated with TG/HDL ratio after adjustment for age and DBP. Conclusion Higher TG/HDL-C ratio is correlated with muscle mass in T2DM patients.https://doi.org/10.1186/s12902-023-01349-8Triglyceride/high-density lipoprotein cholesterol ratioSkeletal muscle indexType 2 diabetes mellitus |
| spellingShingle | Qingsong Fu Zhenwen Zhang Wenchao Hu Yinrong Yang The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients BMC Endocrine Disorders Triglyceride/high-density lipoprotein cholesterol ratio Skeletal muscle index Type 2 diabetes mellitus |
| title | The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| title_full | The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| title_fullStr | The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| title_full_unstemmed | The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| title_short | The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| title_sort | correlation of triglyceride high density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients |
| topic | Triglyceride/high-density lipoprotein cholesterol ratio Skeletal muscle index Type 2 diabetes mellitus |
| url | https://doi.org/10.1186/s12902-023-01349-8 |
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