Nanosecond PEF Induces Oxidative Stress and Apoptosis via Proteasomal Activity Inhibition in Gastric Adenocarcinoma Cells with Drug Resistance

Nanosecond PEF Induces Oxidative Stress and Apoptosis via Proteasomal Activity Inhibition in Gastric Adenocarcinoma Cells with Drug Resistance

Nanosecond (ns) pulsed electric field (PEF) is a technology in which the application of ultra-short electrical pulses can be used to disrupt the barrier function of cell plasma and internal membranes. Disruptions of the membrane integrity cause a substantial imbalance in cell homeostasis in which ox...

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Bibliographic Details
Main Authors: Julita Kulbacka, Nina Rembiałkowska, Anna Szewczyk, Joanna Rossowska, Małgorzata Drąg-Zalesińska, Marek Kulbacki, Anna Choromańska
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
gastric adenocarcinoma
drug resistance
nsPEF
calcium ions
apoptosis
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/23/21/12943

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