Dialysis for acute kidney injury associated with influenza a (H1N1) infection
In June 2009, the World Health Organization declared a novel influenza A, S-OIV (H1N1), pandemic. We observed 44 consecutive patients during the "first wave" of the pandemic. 70.5% of them showed co-morbidities (hypertension, obesity, chronic respiratory diseases, chronic renal disease, di...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2013;volume=24;issue=3;spage=527;epage=533;aulast=Vallejos |
| _version_ | 1811340438597009408 |
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| author | Augusto Vallejos Marcelo Arias Ana Cusumano Eduardo Coste Miguel Simon Ricardo Martinez Sandra Mendez Miguel Raño Luis Sintado Bruno Lococo Carlos Blanco Jorge Cestari |
| author_facet | Augusto Vallejos Marcelo Arias Ana Cusumano Eduardo Coste Miguel Simon Ricardo Martinez Sandra Mendez Miguel Raño Luis Sintado Bruno Lococo Carlos Blanco Jorge Cestari |
| author_sort | Augusto Vallejos |
| collection | DOAJ |
| description | In June 2009, the World Health Organization declared a novel influenza A, S-OIV (H1N1), pandemic. We observed 44 consecutive patients during the "first wave" of the pandemic. 70.5% of them showed co-morbidities (hypertension, obesity, chronic respiratory diseases, chronic renal disease, diabetes, pregnancy). Serious cases were admitted to the intensive care unit (ICU), particularly those with severe acute respiratory failure. Some of them developed acute kidney injury (AKI) and required renal replacement therapy (RRT). The average time between admission to the ICU and initiation of RRT was 3.16 ± 2.6 days. At initiation of RRT, most patients required mechanical ventilation. No relationship was found with creatinine-kinase levels. Seventy-five percent of the cases were observed during a 3-week period and mortality, related to respiratory failure, doubling of alanine amino transferase and use of inotropics was 81.8%. In conclusion, the H1N1-infected patients who developed RRT-requiring AKI, in the context of multi-organ failure, showed a high mortality rate. Thus, it is mandatory that elaborate strategies aimed at anticipating potential renal complications associated to future pandemics are implemented. |
| first_indexed | 2024-04-13T18:41:58Z |
| format | Article |
| id | doaj.art-d0a67f832b094ec4aab27e61e63b98f3 |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-04-13T18:41:58Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-d0a67f832b094ec4aab27e61e63b98f32022-12-22T02:34:42ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422013-01-0124352753310.4103/1319-2442.111045Dialysis for acute kidney injury associated with influenza a (H1N1) infectionAugusto VallejosMarcelo AriasAna CusumanoEduardo CosteMiguel SimonRicardo MartinezSandra MendezMiguel RañoLuis SintadoBruno LococoCarlos BlancoJorge CestariIn June 2009, the World Health Organization declared a novel influenza A, S-OIV (H1N1), pandemic. We observed 44 consecutive patients during the "first wave" of the pandemic. 70.5% of them showed co-morbidities (hypertension, obesity, chronic respiratory diseases, chronic renal disease, diabetes, pregnancy). Serious cases were admitted to the intensive care unit (ICU), particularly those with severe acute respiratory failure. Some of them developed acute kidney injury (AKI) and required renal replacement therapy (RRT). The average time between admission to the ICU and initiation of RRT was 3.16 ± 2.6 days. At initiation of RRT, most patients required mechanical ventilation. No relationship was found with creatinine-kinase levels. Seventy-five percent of the cases were observed during a 3-week period and mortality, related to respiratory failure, doubling of alanine amino transferase and use of inotropics was 81.8%. In conclusion, the H1N1-infected patients who developed RRT-requiring AKI, in the context of multi-organ failure, showed a high mortality rate. Thus, it is mandatory that elaborate strategies aimed at anticipating potential renal complications associated to future pandemics are implemented.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2013;volume=24;issue=3;spage=527;epage=533;aulast=Vallejos |
| spellingShingle | Augusto Vallejos Marcelo Arias Ana Cusumano Eduardo Coste Miguel Simon Ricardo Martinez Sandra Mendez Miguel Raño Luis Sintado Bruno Lococo Carlos Blanco Jorge Cestari Dialysis for acute kidney injury associated with influenza a (H1N1) infection Saudi Journal of Kidney Diseases and Transplantation |
| title | Dialysis for acute kidney injury associated with influenza a (H1N1) infection |
| title_full | Dialysis for acute kidney injury associated with influenza a (H1N1) infection |
| title_fullStr | Dialysis for acute kidney injury associated with influenza a (H1N1) infection |
| title_full_unstemmed | Dialysis for acute kidney injury associated with influenza a (H1N1) infection |
| title_short | Dialysis for acute kidney injury associated with influenza a (H1N1) infection |
| title_sort | dialysis for acute kidney injury associated with influenza a h1n1 infection |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2013;volume=24;issue=3;spage=527;epage=533;aulast=Vallejos |
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