Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry
Objectives:To evaluate the pupillary light reflex responses in patients with unilateral strabismic and anisometropic amblyopia using dynamic pupillometry.Materials and Methods:A total of 102 eyes of 51 patients with unilateral amblyopia were included in this cross-sectional study. Of the 51 patients...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2019-12-01
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| Series: | Türk Oftalmoloji Dergisi |
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http://www.oftalmoloji.org/archives/archive-detail/article-preview/evaluation-of-pupillary-light-reflex-in-amblyopic-/34572
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| _version_ | 1828031049638084608 |
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| author | Gülfidan Bitirgen Mohammed Daraghma Ahmet Özkağnıcı |
| author_facet | Gülfidan Bitirgen Mohammed Daraghma Ahmet Özkağnıcı |
| author_sort | Gülfidan Bitirgen |
| collection | DOAJ |
| description | Objectives:To evaluate the pupillary light reflex responses in patients with unilateral strabismic and anisometropic amblyopia using dynamic pupillometry.Materials and Methods:A total of 102 eyes of 51 patients with unilateral amblyopia were included in this cross-sectional study. Of the 51 patients, 37 (72.5%) had strabismic amblyopia and 14 (27.5%) had anisometropic amblyopia. All patients underwent complete ophthalmological examination, and pupillary light reflex responses were measured using a computerized dynamic pupillometry system (MonPack One; Metrovision, France). Initial pupil diameter; the amplitude, latency, duration, and velocity of pupil contraction; and the latency, duration, and velocity of pupil dilation were recorded. Results obtained from the patients’ amblyopic and normal fellow eyes were compared using paired-samples t-test and Wilcoxon signed rank test.Results:The mean age of the patients was 11.9±6.0 years. Amblyopic eyes had longer contraction latency (p=0.009), shorter contraction duration (p=0.002), and higher dilation velocity (p=0.033) compared to fellow eyes, while other parameters did not show significant differences. In subgroup analysis, eyes with strabismic amblyopia had longer contraction latency (p=0.006) and shorter contraction duration (p=0.017), while eyes with anisometropic amblyopia had shorter contraction duration (p=0.030) when compared with fellow eyes.Conclusion:In this study, the objective records obtained by dynamic pupillometry showed that pupillary light reflex responses are affected in amblyopic eyes. This finding may shed light on unclear aspects of the pathophysiology of amblyopia. |
| first_indexed | 2024-04-10T14:39:51Z |
| format | Article |
| id | doaj.art-d0a69fe4991f4e8c979aac97f5ceec32 |
| institution | Directory Open Access Journal |
| issn | 1300-0659 2147-2661 |
| language | English |
| last_indexed | 2024-04-10T14:39:51Z |
| publishDate | 2019-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Oftalmoloji Dergisi |
| spelling | doaj.art-d0a69fe4991f4e8c979aac97f5ceec322023-02-15T16:08:16ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612019-12-0149631031410.4274/tjo.galenos.2019.3274813049054Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic PupillometryGülfidan Bitirgen0Mohammed Daraghma1Ahmet Özkağnıcı2 Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Konya, Türkiye Özel Reyhanlı Sevgi Hastanesi, Göz Hastalıkları Kliniği, Hatay, Türkiye Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Konya, Türkiye Objectives:To evaluate the pupillary light reflex responses in patients with unilateral strabismic and anisometropic amblyopia using dynamic pupillometry.Materials and Methods:A total of 102 eyes of 51 patients with unilateral amblyopia were included in this cross-sectional study. Of the 51 patients, 37 (72.5%) had strabismic amblyopia and 14 (27.5%) had anisometropic amblyopia. All patients underwent complete ophthalmological examination, and pupillary light reflex responses were measured using a computerized dynamic pupillometry system (MonPack One; Metrovision, France). Initial pupil diameter; the amplitude, latency, duration, and velocity of pupil contraction; and the latency, duration, and velocity of pupil dilation were recorded. Results obtained from the patients’ amblyopic and normal fellow eyes were compared using paired-samples t-test and Wilcoxon signed rank test.Results:The mean age of the patients was 11.9±6.0 years. Amblyopic eyes had longer contraction latency (p=0.009), shorter contraction duration (p=0.002), and higher dilation velocity (p=0.033) compared to fellow eyes, while other parameters did not show significant differences. In subgroup analysis, eyes with strabismic amblyopia had longer contraction latency (p=0.006) and shorter contraction duration (p=0.017), while eyes with anisometropic amblyopia had shorter contraction duration (p=0.030) when compared with fellow eyes.Conclusion:In this study, the objective records obtained by dynamic pupillometry showed that pupillary light reflex responses are affected in amblyopic eyes. This finding may shed light on unclear aspects of the pathophysiology of amblyopia. http://www.oftalmoloji.org/archives/archive-detail/article-preview/evaluation-of-pupillary-light-reflex-in-amblyopic-/34572 amblyopiaanisometropiadynamic pupillometrypupillary light reflexstrabismus |
| spellingShingle | Gülfidan Bitirgen Mohammed Daraghma Ahmet Özkağnıcı Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry Türk Oftalmoloji Dergisi amblyopia anisometropia dynamic pupillometry pupillary light reflex strabismus |
| title | Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry |
| title_full | Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry |
| title_fullStr | Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry |
| title_full_unstemmed | Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry |
| title_short | Evaluation of Pupillary Light Reflex in Amblyopic Eyes Using Dynamic Pupillometry |
| title_sort | evaluation of pupillary light reflex in amblyopic eyes using dynamic pupillometry |
| topic | amblyopia anisometropia dynamic pupillometry pupillary light reflex strabismus |
| url |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/evaluation-of-pupillary-light-reflex-in-amblyopic-/34572
|
| work_keys_str_mv | AT gulfidanbitirgen evaluationofpupillarylightreflexinamblyopiceyesusingdynamicpupillometry AT mohammeddaraghma evaluationofpupillarylightreflexinamblyopiceyesusingdynamicpupillometry AT ahmetozkagnıcı evaluationofpupillarylightreflexinamblyopiceyesusingdynamicpupillometry |