<i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials
The obligate hemiparasite <i>Striga hermonthica</i> is one of the major global biotic threats to agriculture in sub-Saharan Africa, causing severe yield losses of cereals. The germination of <i>Striga</i> seeds relies on host-released signaling molecules, mainly strigolactone...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Plants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2223-7747/11/8/1045 |
| _version_ | 1827627126626451456 |
|---|---|
| author | Muhammad Jamil Jian You Wang Djibril Yonli Tsuyoshi Ota Lamis Berqdar Hamidou Traore Ouedraogo Margueritte Binne Zwanenburg Tadao Asami Salim Al-Babili |
| author_facet | Muhammad Jamil Jian You Wang Djibril Yonli Tsuyoshi Ota Lamis Berqdar Hamidou Traore Ouedraogo Margueritte Binne Zwanenburg Tadao Asami Salim Al-Babili |
| author_sort | Muhammad Jamil |
| collection | DOAJ |
| description | The obligate hemiparasite <i>Striga hermonthica</i> is one of the major global biotic threats to agriculture in sub-Saharan Africa, causing severe yield losses of cereals. The germination of <i>Striga</i> seeds relies on host-released signaling molecules, mainly strigolactones (SLs). This dependency opens up the possibility of deploying SL analogs as “suicidal germination agents” to reduce the accumulated seed bank of <i>Striga</i> in infested soils. Although several synthetic SL analogs have been developed for this purpose, the utility of these compounds in realizing the suicidal germination strategy for combating <i>Striga</i> is still largely unknown. Here, we evaluated the efficacy of three potent SL analogs (MP3, MP16, and Nijmegen-1) under laboratory, greenhouse, and farmer’s field conditions. All investigated analogs showed around a 50% <i>Striga</i> germination rate, equivalent to a 50% reduction in infestation, which was comparable to the standard SL analog GR24. Importantly, MP16 had the maximum reduction of <i>Striga</i> emergence (97%) in the greenhouse experiment, while Nijmegen-1 appeared to be a promising candidate under field conditions, with a 43% and 60% reduction of <i>Striga</i> emergence in pearl millet and sorghum fields, respectively. These findings confirm that the selected SL analogs appear to make promising candidates as simple suicidal agents both under laboratory and real African field conditions, which may support us to improve suicidal germination technology to deplete the <i>Striga</i> seed bank in African agriculture. |
| first_indexed | 2024-03-09T13:08:02Z |
| format | Article |
| id | doaj.art-d0a76769d168490a86a78f7d3042a9bd |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-09T13:08:02Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-d0a76769d168490a86a78f7d3042a9bd2023-11-30T21:46:23ZengMDPI AGPlants2223-77472022-04-01118104510.3390/plants11081045<i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field TrialsMuhammad Jamil0Jian You Wang1Djibril Yonli2Tsuyoshi Ota3Lamis Berqdar4Hamidou Traore5Ouedraogo Margueritte6Binne Zwanenburg7Tadao Asami8Salim Al-Babili9The BioActives Lab, Center for Desert Agriculture, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi ArabiaThe BioActives Lab, Center for Desert Agriculture, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi ArabiaInstitut de l’Environnement et de Recherches Agricoles (INERA), Ouagadougou 04 BP 8645, Burkina FasoApplied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo 113-8657, JapanThe BioActives Lab, Center for Desert Agriculture, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi ArabiaInstitut de l’Environnement et de Recherches Agricoles (INERA), Ouagadougou 04 BP 8645, Burkina FasoInstitut de l’Environnement et de Recherches Agricoles (INERA), Ouagadougou 04 BP 8645, Burkina FasoInstitute for Molecules and Materials, Radboud University, 6525 AJ Nijmegen, The NetherlandsApplied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo 113-8657, JapanThe BioActives Lab, Center for Desert Agriculture, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi ArabiaThe obligate hemiparasite <i>Striga hermonthica</i> is one of the major global biotic threats to agriculture in sub-Saharan Africa, causing severe yield losses of cereals. The germination of <i>Striga</i> seeds relies on host-released signaling molecules, mainly strigolactones (SLs). This dependency opens up the possibility of deploying SL analogs as “suicidal germination agents” to reduce the accumulated seed bank of <i>Striga</i> in infested soils. Although several synthetic SL analogs have been developed for this purpose, the utility of these compounds in realizing the suicidal germination strategy for combating <i>Striga</i> is still largely unknown. Here, we evaluated the efficacy of three potent SL analogs (MP3, MP16, and Nijmegen-1) under laboratory, greenhouse, and farmer’s field conditions. All investigated analogs showed around a 50% <i>Striga</i> germination rate, equivalent to a 50% reduction in infestation, which was comparable to the standard SL analog GR24. Importantly, MP16 had the maximum reduction of <i>Striga</i> emergence (97%) in the greenhouse experiment, while Nijmegen-1 appeared to be a promising candidate under field conditions, with a 43% and 60% reduction of <i>Striga</i> emergence in pearl millet and sorghum fields, respectively. These findings confirm that the selected SL analogs appear to make promising candidates as simple suicidal agents both under laboratory and real African field conditions, which may support us to improve suicidal germination technology to deplete the <i>Striga</i> seed bank in African agriculture.https://www.mdpi.com/2223-7747/11/8/1045germination stimulantwitchweedmethyl phenlactonoates (MPs)Nijmegen-1weed |
| spellingShingle | Muhammad Jamil Jian You Wang Djibril Yonli Tsuyoshi Ota Lamis Berqdar Hamidou Traore Ouedraogo Margueritte Binne Zwanenburg Tadao Asami Salim Al-Babili <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials Plants germination stimulant witchweed methyl phenlactonoates (MPs) Nijmegen-1 weed |
| title | <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials |
| title_full | <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials |
| title_fullStr | <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials |
| title_full_unstemmed | <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials |
| title_short | <i>Striga hermonthica</i> Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials |
| title_sort | i striga hermonthica i suicidal germination activity of potent strigolactone analogs evaluation from laboratory bioassays to field trials |
| topic | germination stimulant witchweed methyl phenlactonoates (MPs) Nijmegen-1 weed |
| url | https://www.mdpi.com/2223-7747/11/8/1045 |
| work_keys_str_mv | AT muhammadjamil istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT jianyouwang istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT djibrilyonli istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT tsuyoshiota istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT lamisberqdar istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT hamidoutraore istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT ouedraogomargueritte istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT binnezwanenburg istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT tadaoasami istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials AT salimalbabili istrigahermonthicaisuicidalgerminationactivityofpotentstrigolactoneanalogsevaluationfromlaboratorybioassaystofieldtrials |