Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature
Background: Papillary lesions of the breast are a heterogeneous group of neoplasms, the diagnosis and treatment of which is challenging. Typically surgical excision is recommended for papillary lesions after core needle biopsy (CNB) to rule out concurrent malignancy when a diagnosis of papilloma wit...
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| Format: | Article |
| Language: | English |
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Kaviani Breast Disease Institute
2020-09-01
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| Series: | Archives of Breast Cancer |
| Subjects: | |
| Online Access: | https://archivesbreastcancer.com/index.php/abc/article/view/311 |
| _version_ | 1818390618009763840 |
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| author | Marzieh Mohammadi Zavieh Farid Azmude Ardalan Farnaz Karimi Nahid Sedighi Ramesh Omranipour Ahmad Elahi |
| author_facet | Marzieh Mohammadi Zavieh Farid Azmude Ardalan Farnaz Karimi Nahid Sedighi Ramesh Omranipour Ahmad Elahi |
| author_sort | Marzieh Mohammadi Zavieh |
| collection | DOAJ |
| description | Background: Papillary lesions of the breast are a heterogeneous group of neoplasms, the diagnosis and treatment of which is challenging. Typically surgical excision is recommended for papillary lesions after core needle biopsy (CNB) to rule out concurrent malignancy when a diagnosis of papilloma with atypia is yielded on CNB. For papilloma without atypia, however, making a decision about excision versus observation is challenging.
Case Presentation: A 14-year-old female with nipple discharge, and a 2 cm mass in the right breast, with the pathology of intra-ductal papilloma without atypia on CNB presented. The question to be answered by multi-disciplinary team was the best management of this papillary lesion and whether the follow up was adequate or excision was mandatory.
Question: What is the best plan for management of the young patient according to the primary pathology report of Juvenile Papillomatosis?
Conclusion: Histoathology review of CNB specimen in rare and high risk lesions may have some advantages. On the other hand, in high risk circumstances, the excision of the lesion is recommended. Thus, in this case, the multi-disciplinary team recommended excision of the lesion. |
| first_indexed | 2024-12-14T05:00:29Z |
| format | Article |
| id | doaj.art-d0ae86e4e4bc4e32b905ae095d531c24 |
| institution | Directory Open Access Journal |
| issn | 2383-0433 |
| language | English |
| last_indexed | 2024-12-14T05:00:29Z |
| publishDate | 2020-09-01 |
| publisher | Kaviani Breast Disease Institute |
| record_format | Article |
| series | Archives of Breast Cancer |
| spelling | doaj.art-d0ae86e4e4bc4e32b905ae095d531c242022-12-21T23:16:15ZengKaviani Breast Disease InstituteArchives of Breast Cancer2383-04332020-09-0110.19187/abc.202073100-103Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the LiteratureMarzieh Mohammadi Zavieh0Farid Azmude Ardalan1Farnaz Karimi2Nahid Sedighi3Ramesh Omranipour4Ahmad Elahi5Department of Surgery, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Alborz University of Medical Sciences, Alborz, Karaj, IranDepartment of Radiology, Tehran University of Medical Sciences, Tehran, IranDepartment of Surgery, Tehran University of Medical Sciences, Tehran, Iran AND Breast Cancer Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Surgery, Alborz of Medical Sciences, Alborz, Karaj, IranBackground: Papillary lesions of the breast are a heterogeneous group of neoplasms, the diagnosis and treatment of which is challenging. Typically surgical excision is recommended for papillary lesions after core needle biopsy (CNB) to rule out concurrent malignancy when a diagnosis of papilloma with atypia is yielded on CNB. For papilloma without atypia, however, making a decision about excision versus observation is challenging. Case Presentation: A 14-year-old female with nipple discharge, and a 2 cm mass in the right breast, with the pathology of intra-ductal papilloma without atypia on CNB presented. The question to be answered by multi-disciplinary team was the best management of this papillary lesion and whether the follow up was adequate or excision was mandatory. Question: What is the best plan for management of the young patient according to the primary pathology report of Juvenile Papillomatosis? Conclusion: Histoathology review of CNB specimen in rare and high risk lesions may have some advantages. On the other hand, in high risk circumstances, the excision of the lesion is recommended. Thus, in this case, the multi-disciplinary team recommended excision of the lesion.https://archivesbreastcancer.com/index.php/abc/article/view/311Papillary lesionBreastAtypia |
| spellingShingle | Marzieh Mohammadi Zavieh Farid Azmude Ardalan Farnaz Karimi Nahid Sedighi Ramesh Omranipour Ahmad Elahi Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature Archives of Breast Cancer Papillary lesion Breast Atypia |
| title | Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature |
| title_full | Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature |
| title_fullStr | Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature |
| title_full_unstemmed | Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature |
| title_short | Papillary Lesion of the Breast in a Young Girl Suspicious to Juvenile Papillomatosis, Clinical Decision Making in a Multi-disciplinary Team and Review of the Literature |
| title_sort | papillary lesion of the breast in a young girl suspicious to juvenile papillomatosis clinical decision making in a multi disciplinary team and review of the literature |
| topic | Papillary lesion Breast Atypia |
| url | https://archivesbreastcancer.com/index.php/abc/article/view/311 |
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