Intra-articular administration of PLGA resveratrol sustained-release nanoparticles attenuates the development of rat osteoarthritis

Our previous studies have confirmed that resveratrol (RSV) can prevent the development of osteoarthritis through a variety of mechanisms, such as apoptosis inhibition, autophagy induction and SIRT 1 activation. However, the pharmaceutical application of RSV is mainly limited by its low bioavailabili...

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Bibliographic Details
Main Authors: Liwei Wei, Qingqing Pan, Junyan Teng, Hong Zhang, Na Qin
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423003447