Genome-scale CRISPR-Cas9 knockout screening in nasopharyngeal carcinoma for radiosensitive and radioresistant genes

Genome-scale CRISPR-Cas9 knockout screening in nasopharyngeal carcinoma for radiosensitive and radioresistant genes

Background: Genome-scale CRISPR-Cas9 knockout screening may provide new insights into the mechanism underlying clinical radioresistance in nasopharyngeal carcinoma (NPC), which is remain largely unknown. Our objective was to screen the functional genes associated with radiosensitivity and radioresis...

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Bibliographic Details
Main Authors: Ziyan Zhou, Gang Chen, Mingjun Shen, Jixi Li, Kang Liu, Ming Liu, Shuo Shi, Dong Yang, Wei Chen, Sixia Chen, Yuanxiu Yin, Yating Qin, Xuejin Su, Weimin Chen, Min Kang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Translational Oncology
Subjects:
Nasopharyngeal carcinoma
Radiosensitivity
Radiaoresistance
CRISPR-cas9
Functional gene
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323000104

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http://www.sciencedirect.com/science/article/pii/S1936523323000104

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