Neural stem cell transplantation inhibits glial cell proliferation and P2X receptor-mediated neuropathic pain in spinal cord injury rats

Neural stem cell transplantation inhibits glial cell proliferation and P2X receptor-mediated neuropathic pain in spinal cord injury rats

P2X4 and P2X7 receptors play an important role in neuropathic pain after spinal cord injury. Regulation of P2X4 and P2X7 receptors can obviously reduce pain hypersensitivity after injury. To investigate the role of neural stem cell transplantation on P2X receptor-mediated neuropathic pain and explor...

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Bibliographic Details
Main Authors: Xiao-Jing Du, Yue-Xia Chen, Zun-Cheng Zheng, Nan Wang, Xiao-Yu Wang, Fan-E Kong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; cell transplantation; sensory nerve function; glial fibrillary acidic protein; neurofilament; P2X4 receptor; P2X7 receptor; microglial cells; perception threshold; hind limb function; glial hyperplasia; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=5;spage=876;epage=885;aulast=Du

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