Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments

Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments

Gliomas are one of the most lethal types of cancers accounting for ∼80% of all central nervous system (CNS) primary malignancies. Among gliomas, glioblastomas (GBM) are the most aggressive, characterized by a median patient survival of fewer than 15  months. Recent molecular characterization studies...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mahmoud S. Alghamri, Brandon L. McClellan, Carson S. Hartlage, Santiago Haase, Syed Mohd Faisal, Rohit Thalla, Ali Dabaja, Kaushik Banerjee, Stephen V. Carney, Anzar A. Mujeeb, Michael R. Olin, James J. Moon, Anna Schwendeman, Pedro R. Lowenstein, Maria G. Castro
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2021-05-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
immunosuppression
inflammation
tumor microenvironment
glioma
immunotherapy
Online Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2021.680021/full

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