Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity
Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship between the hepatic insulin resistance-associated signaling elements and PDEs together...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2022-05-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2021-0180 |
| _version_ | 1818548684073205760 |
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| author | Pektaş Mehmet Bilgehan Aslan Esra Güzel Hilal Korkmaz Ömer Adil Çeleğen Kübra Pektaş Ayhan Bostanci Aykut Sadi Gökhan |
| author_facet | Pektaş Mehmet Bilgehan Aslan Esra Güzel Hilal Korkmaz Ömer Adil Çeleğen Kübra Pektaş Ayhan Bostanci Aykut Sadi Gökhan |
| author_sort | Pektaş Mehmet Bilgehan |
| collection | DOAJ |
| description | Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship between the hepatic insulin resistance-associated signaling elements and PDEs together with inflammatory markers and investigates the role of kefir in the treatment. |
| first_indexed | 2024-12-12T08:23:28Z |
| format | Article |
| id | doaj.art-d0c4073ae78642a29d1de7e1fa680ab6 |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-12-12T08:23:28Z |
| publishDate | 2022-05-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-d0c4073ae78642a29d1de7e1fa680ab62022-12-22T00:31:20ZengDe GruyterTürk Biyokimya Dergisi1303-829X2022-05-0147334935810.1515/tjb-2021-0180Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivityPektaş Mehmet Bilgehan0Aslan Esra1Güzel Hilal2Korkmaz Ömer Adil3Çeleğen Kübra4Pektaş Ayhan5Bostanci Aykut6Sadi Gökhan7Afyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyAfyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyAfyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyYildiz Teknik Universitesi, Istanbul, TurkeyAfyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyAfyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyDepartment of Biology, Karamanoğlu Mehmetbey Üniversitesi, Karaman, Merkez, TurkeyDepartment of Biology, Karamanoğlu Mehmetbey Üniversitesi, Karaman, Merkez, TurkeyPhosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship between the hepatic insulin resistance-associated signaling elements and PDEs together with inflammatory markers and investigates the role of kefir in the treatment.https://doi.org/10.1515/tjb-2021-0180hfcsinflammationinsulin signaling pathwaykefirphosphodiesteraseyfmskefirfosfodiesterazinsülin sinyal yoluinflamasyon |
| spellingShingle | Pektaş Mehmet Bilgehan Aslan Esra Güzel Hilal Korkmaz Ömer Adil Çeleğen Kübra Pektaş Ayhan Bostanci Aykut Sadi Gökhan Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity Türk Biyokimya Dergisi hfcs inflammation insulin signaling pathway kefir phosphodiesterase yfms kefir fosfodiesteraz insülin sinyal yolu inflamasyon |
| title | Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| title_full | Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| title_fullStr | Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| title_full_unstemmed | Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| title_short | Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| title_sort | kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity |
| topic | hfcs inflammation insulin signaling pathway kefir phosphodiesterase yfms kefir fosfodiesteraz insülin sinyal yolu inflamasyon |
| url | https://doi.org/10.1515/tjb-2021-0180 |
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