Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with episodes of inflammatory demyelination and remyelination. While remyelination has been linked with functional recovery in MS patients, there is evidence of ongoing tissue damage despite complete myelin...

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Autors principals: Jiangshan Zhan, Florian Nepomuk Fegg, Hannes Kaddatz, Sebastian Rühling, Julia Frenz, Bernd Denecke, Sandra Amor, Peter Ponsaerts, Tanja Hochstrasser, Markus Kipp
Format: Article
Idioma:English
Publicat: Elsevier 2021-07-01
Col·lecció:Neurobiology of Disease
Matèries:
Multiple sclerosis
Gliosis
Axonal damage
Remyelination
Protein kinase c delta
Accés en línia:http://www.sciencedirect.com/science/article/pii/S0969996121001200

Internet

http://www.sciencedirect.com/science/article/pii/S0969996121001200

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