Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with episodes of inflammatory demyelination and remyelination. While remyelination has been linked with functional recovery in MS patients, there is evidence of ongoing tissue damage despite complete myelin...

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Detalles Bibliográficos
Autores principales: Jiangshan Zhan, Florian Nepomuk Fegg, Hannes Kaddatz, Sebastian Rühling, Julia Frenz, Bernd Denecke, Sandra Amor, Peter Ponsaerts, Tanja Hochstrasser, Markus Kipp
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2021-07-01
Colección:Neurobiology of Disease
Materias:
Multiple sclerosis
Gliosis
Axonal damage
Remyelination
Protein kinase c delta
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S0969996121001200

Internet

http://www.sciencedirect.com/science/article/pii/S0969996121001200

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