Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with episodes of inflammatory demyelination and remyelination. While remyelination has been linked with functional recovery in MS patients, there is evidence of ongoing tissue damage despite complete myelin...

Полное описание

Библиографические подробности
Главные авторы: Jiangshan Zhan, Florian Nepomuk Fegg, Hannes Kaddatz, Sebastian Rühling, Julia Frenz, Bernd Denecke, Sandra Amor, Peter Ponsaerts, Tanja Hochstrasser, Markus Kipp
Формат: Статья
Язык:English
Опубликовано: Elsevier 2021-07-01
Серии:Neurobiology of Disease
Предметы:
Multiple sclerosis
Gliosis
Axonal damage
Remyelination
Protein kinase c delta
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S0969996121001200

Internet

http://www.sciencedirect.com/science/article/pii/S0969996121001200

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