The effect of opioids on gastrointestinal function in the ICU
Abstract Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-10-01
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| Series: | Critical Care |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13054-021-03793-1 |
| _version_ | 1818732386505981952 |
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| author | Yun Yan Yu Chen Xijing Zhang |
| author_facet | Yun Yan Yu Chen Xijing Zhang |
| author_sort | Yun Yan |
| collection | DOAJ |
| description | Abstract Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains uncertain in the ICU. This review aims to describe the effect of opioids on GI motility, their potential risk of increasing infection and the treatment of GI dysmotility with opioid antagonists in the ICU setting. |
| first_indexed | 2024-12-17T23:32:45Z |
| format | Article |
| id | doaj.art-d0c7270cfa8a4921a37b97ccc09c7ee5 |
| institution | Directory Open Access Journal |
| issn | 1364-8535 |
| language | English |
| last_indexed | 2024-12-17T23:32:45Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Critical Care |
| spelling | doaj.art-d0c7270cfa8a4921a37b97ccc09c7ee52022-12-21T21:28:38ZengBMCCritical Care1364-85352021-10-0125111410.1186/s13054-021-03793-1The effect of opioids on gastrointestinal function in the ICUYun Yan0Yu Chen1Xijing Zhang2Department of Anaesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical UniversityDepartment of Anaesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical UniversityDepartment of Anaesthesiology and Perioperative Medicine, Xijing Hospital, The Fourth Military Medical UniversityAbstract Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains uncertain in the ICU. This review aims to describe the effect of opioids on GI motility, their potential risk of increasing infection and the treatment of GI dysmotility with opioid antagonists in the ICU setting.https://doi.org/10.1186/s13054-021-03793-1OpioidsCritical illnessGastrointestinal functionGastrointestinal microbiome |
| spellingShingle | Yun Yan Yu Chen Xijing Zhang The effect of opioids on gastrointestinal function in the ICU Critical Care Opioids Critical illness Gastrointestinal function Gastrointestinal microbiome |
| title | The effect of opioids on gastrointestinal function in the ICU |
| title_full | The effect of opioids on gastrointestinal function in the ICU |
| title_fullStr | The effect of opioids on gastrointestinal function in the ICU |
| title_full_unstemmed | The effect of opioids on gastrointestinal function in the ICU |
| title_short | The effect of opioids on gastrointestinal function in the ICU |
| title_sort | effect of opioids on gastrointestinal function in the icu |
| topic | Opioids Critical illness Gastrointestinal function Gastrointestinal microbiome |
| url | https://doi.org/10.1186/s13054-021-03793-1 |
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