DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer

DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer

Breast cancer is one of the most common malignancies in women worldwide. In breast cancer, the cell proliferation rate is known to influence the cancer malignancy. Recent studies have shown that DNA replication initiation/licensing factors are involved in cancer cell proliferation as well as cancer...

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Bibliographic Details
Main Authors: Ravikiran Mahadevappa, Henrique Neves, Shun Ming Yuen, Muhammad Jameel, Yuchen Bai, Hiu-Fung Yuen, Shu-Dong Zhang, Youzhi Zhu, Yao Lin, Hang Fai Kwok
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
MCM10
breast cancer
knockdown
overexpression
proliferation
survival
Online Access:http://www.mdpi.com/2072-6694/10/9/282

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