The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus

Emerging viral infections are a ceaseless challenge and remain a global public health concern. The world has not yet come back to normal from the devastating effects of the highly contagious and pathogenic novel coronavirus, or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Olfactory...

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Main Authors: Sareesh Naduvil Narayanan, Pooja Shivappa, Sreeshma Padiyath, Anand Bhaskar, Yan Wa Li, Tarig Hakim Merghani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.839182/full
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author Sareesh Naduvil Narayanan
Pooja Shivappa
Sreeshma Padiyath
Anand Bhaskar
Yan Wa Li
Tarig Hakim Merghani
author_facet Sareesh Naduvil Narayanan
Pooja Shivappa
Sreeshma Padiyath
Anand Bhaskar
Yan Wa Li
Tarig Hakim Merghani
author_sort Sareesh Naduvil Narayanan
collection DOAJ
description Emerging viral infections are a ceaseless challenge and remain a global public health concern. The world has not yet come back to normal from the devastating effects of the highly contagious and pathogenic novel coronavirus, or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Olfactory and taste dysfunction is common in patients infected by the novel coronavirus. In light of the emergence of different coronavirus variants, it is important to update the prevalence and pathophysiology of these side effects. In this review, articles published on the prevalence of olfactory and taste dysfunction from coronavirus disease (COVID-19) and their possible pathophysiologic mechanisms have been reviewed and reported. The modulatory role of different SARS-CoV-2 variants on the chemical senses is then described. The clinical relevance of chemical sense disorder and its long-term morbidity and management is also discussed.
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spelling doaj.art-d0d2d9143ccd46a58a5718e03e0834c02022-12-22T00:55:00ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-06-011010.3389/fpubh.2022.839182839182The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel CoronavirusSareesh Naduvil Narayanan0Pooja Shivappa1Sreeshma Padiyath2Anand Bhaskar3Yan Wa Li4Tarig Hakim Merghani5Department of Physiology, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, United Arab EmiratesDepartment of Basic Sciences, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, United Arab EmiratesIndependent Microbiology Researcher, Ras Al Khaimah, United Arab EmiratesDepartment of Biomedical Sciences, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau SAR, ChinaDepartment of Biomedical Sciences, Faculty of Medicine, Macau University of Science and Technology, Taipa, Macau SAR, ChinaDepartment of Physiology, Ras Al Khaimah College of Medical Sciences, Ras Al Khaimah Medical and Health Sciences University, Ras Al Khaimah, United Arab EmiratesEmerging viral infections are a ceaseless challenge and remain a global public health concern. The world has not yet come back to normal from the devastating effects of the highly contagious and pathogenic novel coronavirus, or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Olfactory and taste dysfunction is common in patients infected by the novel coronavirus. In light of the emergence of different coronavirus variants, it is important to update the prevalence and pathophysiology of these side effects. In this review, articles published on the prevalence of olfactory and taste dysfunction from coronavirus disease (COVID-19) and their possible pathophysiologic mechanisms have been reviewed and reported. The modulatory role of different SARS-CoV-2 variants on the chemical senses is then described. The clinical relevance of chemical sense disorder and its long-term morbidity and management is also discussed.https://www.frontiersin.org/articles/10.3389/fpubh.2022.839182/fullnovel coronavirus disease (COVID-19)angiotensin-converting enzyme 2 receptor (ACE-2)chemical sensesolfactory dysfunctiontaste dysfunction
spellingShingle Sareesh Naduvil Narayanan
Pooja Shivappa
Sreeshma Padiyath
Anand Bhaskar
Yan Wa Li
Tarig Hakim Merghani
The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
Frontiers in Public Health
novel coronavirus disease (COVID-19)
angiotensin-converting enzyme 2 receptor (ACE-2)
chemical senses
olfactory dysfunction
taste dysfunction
title The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
title_full The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
title_fullStr The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
title_full_unstemmed The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
title_short The Prevalence and Pathophysiology of Chemical Sense Disorder Caused by the Novel Coronavirus
title_sort prevalence and pathophysiology of chemical sense disorder caused by the novel coronavirus
topic novel coronavirus disease (COVID-19)
angiotensin-converting enzyme 2 receptor (ACE-2)
chemical senses
olfactory dysfunction
taste dysfunction
url https://www.frontiersin.org/articles/10.3389/fpubh.2022.839182/full
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