Gait Analysis for Early Detection of Motor Symptoms in the 6-OHDA Rat Model of Parkinson's Disease

Gait Analysis for Early Detection of Motor Symptoms in the 6-OHDA Rat Model of Parkinson's Disease

Computer-supported gait analysis has proven to be effective for the comprehensive assessment of gait changes in rodent models of neurodegenerative and neurological disorders. However, full characterization of individual gait parameters is required for specific neurological or neurodegenerative disor...

Full description

Bibliographic Details
Main Authors:	Jordi Boix, Daniela von Hieber, Bronwen Connor
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-03-01
Series:	Frontiers in Behavioral Neuroscience
Subjects:	gait analysis Parkinson's disease 6-hydroxydopamine lesion substantia nigra pars compacta midbrain dopamine neurons motor deficiencies
Online Access:	http://journal.frontiersin.org/article/10.3389/fnbeh.2018.00039/full

Similar Items

The dosage of curcumin to alleviate movement symptoms in a 6-hydroxydopamine-induced Parkinson's disease rat model
by: Xiaoyu Liu, et al.
Published: (2023-06-01)

Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease
by: V. Rizelio, et al.
Published: (2010-01-01)

Oxidative Stress and Genetics in the Pathogenesis of Parkinson's Disease
by: Yi Zhang, et al.
Published: (2000-08-01)

A Multi-Scale Computational Model of Levodopa-Induced Toxicity in Parkinson's Disease
by: Vignayanandam Ravindernath-Jayashree Muddapu, et al.
Published: (2022-04-01)

Habitual behavior and dopamine cell vulnerability in Parkinson disease
by: Ledia eF. Hernandez, et al.
Published: (2015-11-01)

Can Interactions Between α-Synuclein, Dopamine and Calcium Explain Selective Neurodegeneration in Parkinson's Disease?
by: Michael R. Post, et al.
Published: (2018-03-01)

Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age
by: Giulia Costa, et al.
Published: (2018-05-01)

Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on l-Dopa induced dyskinesia
by: Peggy Rentsch, et al.
Published: (2019-02-01)

From the axons of the SNc dopamine neurons to their dendritic processes: further clues to susceptibility in Parkinson’s disease (PD)?
by: Eleftheria Kyriaki Pissadaki
Published: (2014-04-01)

EL NÚCLEO PEDUNCULOPONTINO Y SU RELACIÓN CON LA FISIOPATOLOGÍA DE LA ENFERMEDAD DE PARKINSON
by: LISETTE BLANCO LEZCANO, et al.
Published: (2012-09-01)

Spatial RNA Sequencing Identifies Robust Markers of Vulnerable and Resistant Human Midbrain Dopamine Neurons and Their Expression in Parkinson’s Disease
by: Julio Aguila, et al.
Published: (2021-07-01)

State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons
by: Valentina Basso, et al.
Published: (2024-09-01)

Sporadic midbrain dopamine neuron abnormalities in laboratory mice
by: Kavita Prasad, et al.
Published: (2008-11-01)

A Multi-Scale Computational Model of Excitotoxic Loss of Dopaminergic Cells in Parkinson's Disease
by: Vignayanandam Ravindernath Muddapu, et al.
Published: (2020-09-01)

Short-echo-time magnitude image derived from quantitative susceptibility mapping could resemble neuromelanin-sensitive MRI image in substantia nigra
by: Xue Ling Liu, et al.
Published: (2020-06-01)

Effects of Chemogenetic Inhibition of D1 or D2 Receptor-Containing Neurons of the Substantia Nigra and Striatum in Mice With Tourette Syndrome
by: Lixue Lin, et al.
Published: (2021-12-01)

Lesión neurotóxica unilateral del núcleo pedunculopontino: buen acercamiento a un modelo experimental presintomático de enfermedad de Parkinson en ratas
by: Lisette Blanco Lezcano, et al.
Published: (2020-12-01)

Ethanol extract of Epipremnum aureum leaves attenuate intranigral-rotenone induced Parkinson’s disease in rats.
by: Suraj Sood, et al.
Published: (2020-05-01)

Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson’s Disease
by: Sarah Plum, et al.
Published: (2020-12-01)

Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease
by: Gian-Carlo Eyer, et al.
Published: (2021-11-01)

Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinson's disease
by: Naying He, et al.
Published: (2020-01-01)

Altered Development of Mesencephalic Dopaminergic Neurons in SIDS: New Insights into Understanding Sudden Infant Death Pathogenesis
by: Anna Maria Lavezzi
Published: (2021-10-01)

Parkinson’s Disease and the COVID-19 Pandemic: A Review Article on the Association between SARS-CoV-2 and α-Synucleinopathy
by: Smriti Sinha, et al.
Published: (2021-09-01)

Separate groups of dopamine neurons innervate caudate head and tail encoding flexible and stable value memories
by: Hyoung F Kim, et al.
Published: (2014-10-01)

Toll-like Receptor 4 Is Upregulated in Parkinson’s Disease Patients and Co-Localizes with pSer129αSyn: A Possible Link with the Pathology
by: Carmela Conte, et al.
Published: (2023-05-01)

Activation and polarization of striatal microglia and astrocytes are involved in bradykinesia and allodynia in early-stage parkinsonian mice
by: Xue Zhang, et al.
Published: (2024-07-01)

Effects of Acupuncture on Behavioral Stereotypies and Brain Dopamine System in Mice as a Model of Tourette Syndrome
by: Lixue Lin, et al.
Published: (2019-10-01)

Gentle handling temporarily increases c-Fos in the substantia nigra pars compacta
by: C.A. Santos, et al.
Published: (2008-10-01)

Dopamine and the Brainstem Locomotor Networks: From Lamprey to Human
by: Dimitri Ryczko, et al.
Published: (2017-05-01)

A Multiscale, Systems-Level, Neuropharmacological Model of Cortico-Basal Ganglia System for Arm Reaching Under Normal, Parkinsonian, and Levodopa Medication Conditions
by: Sandeep Sathyanandan Nair, et al.
Published: (2022-01-01)

Peripheral inflammation and neuroprotection: Systemic pretreatment with complete Freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of Parkinson's disease
by: Marie-Thérèse Armentero, et al.
Published: (2006-12-01)

Diagnosing Parkinson's disease by combining neuromelanin and iron imaging features using an automated midbrain template approach
by: Mojtaba Jokar, et al.
Published: (2023-02-01)

A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity
by: Vignayanandam Ravindernath Muddapu, et al.
Published: (2019-02-01)

Enduring, Sexually Dimorphic Impact of In Utero Exposure to Elevated Levels of Glucocorticoids on Midbrain Dopaminergic Populations
by: Glenda E. Gillies, et al.
Published: (2016-12-01)

Application of the Catecholaminergic Neuron Electron Transport (CNET) Physical Substrate for Consciousness and Action Selection to Integrated Information Theory
by: Chris Rourk
Published: (2022-01-01)

Increased Serum Lithium Level due to Mild to Moderate damage to Dopaminergic Neurons of the Substantia Nigra, Evidence from Animal Model of Parkinson’s Disease induced by 6-Hydoxydopamine
by: Mohammad Hossein Esmaeili, et al.
Published: (2022-12-01)

Integrating the Roles of Midbrain Dopamine Circuits in Behavior and Neuropsychiatric Disease
by: Allen PF Chen, et al.
Published: (2021-06-01)

Racing and Pacing in the Reward System: A Multi-Clock Circadian Control Over Dopaminergic Signalling
by: Kamil Pradel, et al.
Published: (2022-06-01)

Cell-autonomous role of leucine-rich repeat kinase in the protection of dopaminergic neuron survival
by: Jongkyun Kang, et al.
Published: (2024-06-01)

Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding
by: Véronne A. J. de Vrind, et al.
Published: (2021-07-01)