ΔPSap4#5 surface-functionalized abiraterone-loaded nanoparticle successfully inhibits carcinogen-induced prostate cancer in mice: a mechanistic investigation

ΔPSap4#5 surface-functionalized abiraterone-loaded nanoparticle successfully inhibits carcinogen-induced prostate cancer in mice: a mechanistic investigation

Abstract Prostate cancer (PCa) is one of the fatal illnesses among males globally. PCa-treatment does not include radiotherapy. Chemotherapy eventually causes drug resistance, disease recurrence, metastatic advancement, multi-organ failure, and death. Preclinical data on PCa-induced by carcinogens a...

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Bibliographic Details
Main Authors: Ashique Al Hoque, Debasmita Dutta, Brahamacharry Paul, Leena Kumari, Iman Ehsan, Moumita Dhara, Biswajit Mukherjee, Mohiuddin Quadir, Benny Abraham Kaipparettu, Soumik Laha, Shantanu Ganguly
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cancer Nanotechnology
Subjects:
Aptamer-mediated tumor targeting
Prostate-specific membrane antigen (PSMA)
Abiraterone acetate
Prostate cancer therapy
Pharmacokinetics
Online Access:https://doi.org/10.1186/s12645-023-00223-5

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