Morphofunctional markers of the efficiency stimulated by the pool proliferation of the nasal mucosa cells in patients with polyposis rinosinusitis
Background. The article highlights potential pathomorphological and pathophysiological mechanisms of effective treatment of polypous rhinosinusitis. Materials and methods. The study included patients diagnosed with bilateral polyposis rhinosinusitis, who were conducted immunohistochemical analysi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penza State University Publishing House
2022-06-01
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| Series: | Известия высших учебных заведений. Поволжский регион: Медицинские науки |
| Subjects: |
| Summary: | Background. The article highlights potential pathomorphological and pathophysiological
mechanisms of effective treatment of polypous rhinosinusitis. Materials and
methods. The study included patients diagnosed with bilateral polyposis rhinosinusitis, who
were conducted immunohistochemical analysis of TLR9 expression using monoclonal antibodies
in biopsy postoperative material (twice: prior to treatment and 20 days after treatment),
and cytological examination of nasal reprint smears stained by Romanovsky-Giemsa
method (immersion microscopy 7×90). Results. The study detected individual features of
the proliferative activity of the epithelial pool of the nasal mucosa and pathological polyposis
tissue in response to complex immunocorrective therapy. Conclusions. The results obtained
allow including immunocorrective therapy in the complex treatment of polyposis
rhinosinusitis to reduce possible relapses of the pathology. |
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| ISSN: | 2072-3032 |