| Summary: | Abstract Background To investigate the secular trends in breast cancer burden with attributable risk factors, and make projections over time, which would contribute to the control and prevention of breast cancer. Methods We extracted detailed data on breast cancer incident cases and age‐standardized incidence rate (ASIR), deaths and age‐standardized mortality rate (ASMR), disability‐adjusted life‐years (DALYs), and age‐standardized DALYs rate (ASDR), as well as the attributable risk factors in China from the Global Burden of Diseases Study 2019. The estimated annual percentage change (EAPC) was calculated to quantify the changing trends. The national DALYs attributable to Socio‐demographic Index (SDI) values were also presented. Projections to 2030 were estimated using the Bayesian age‐period‐cohort model. Results From 1990 to 2019, the number of breast cancer incident cases increased fourfold to 375,484, with deaths and DALYs over doubling to 96.306 and 2,957,454, respectively. The ASIR (EAPC = 2.84; 95% CI, 2.74–2.95) and ASMR (EAPC = 0.06; 95% CI, 0.00–0.12) increased, while the ASDR decreased with the EAPC of −0.13 (95% CI, −0.19 to −0.06) at the same period. The ASDR varied across provincial regions, which appeared to be in a wave‐like upcurve with SDI values increasing. High body mass index became the first contribution to breast cancer DALYs for females in 2019, and alcohol use for males. Breast Cancer incident cases and deaths would increase to 587.7 and 125.6 thousand in 2030, of which there will be 577.1 and 122.7 thousand for females, and 10.6 and 2.9 thousand for males, respectively. Conclusion Breast cancer remains a major public health problem in China. The absolute burden has been increasing over time, and varied across sex and regions. To control the potential risk factors and develop specific strategies will help to reduce the disease burden.
|
|---|