Activating SIRT-1 Signalling with the Mitochondrial-CoQ10 Activator Solanesol Improves Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder
Bipolar disorder (BD) is a chronic mental illness characterized by mood fluctuations that range from depressive lows to manic highs. Several studies have linked the downregulation of SIRT-1 (silent mating type information regulation-2 homologs) signaling to the onset of BD and other neurological dys...
Main Authors: | Bidisha Rajkhowa, Sidharth Mehan, Pranshul Sethi, Aradhana Prajapati, Manisha Suri, Sumit Kumar, Sonalika Bhalla, Acharan S. Narula, Abdulrahman Alshammari, Metab Alharbi, Nora Alkahtani, Saeed Alghamdi, Reni Kalfin |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/15/8/959 |
Similar Items
-
Synthesis of Molecularly Imprinted Polymer via Emulsion Polymerization for Application in Solanesol Separation
by: Guojie Zhao, et al.
Published: (2020-04-01) -
Solanesol alleviates metal oxide nanoparticles generated toxicity in human placental BeWo cells
by: Rashid Lateef, et al.
Published: (2023-12-01) -
Smo-Shh Agonist Purmorphamine Prevents Neurobehavioral and Neurochemical Defects in 8-OH-DPAT-Induced Experimental Model of Obsessive-Compulsive Disorder
by: Ria Gupta, et al.
Published: (2022-03-01) -
Solanesol sequential extraction from tobacco leaves using microwave-ultrasound-assisted extraction (MUAE): MAE optimization
by: Edwin Rizki Safitra, et al.
Published: (2024-01-01) -
Ouabain Promotes Gap Junctional Intercellular Communication in Cancer Cells
by: Mauricio Serrano-Rubi, et al.
Published: (2020-12-01)