A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus
This was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was as...
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MDPI AG
2022-05-01
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| Online Access: | https://www.mdpi.com/2072-6643/14/10/2011 |
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| author | Jiaxing Tan Nuozhou Liu Peiyan Sun Yi Tang Wei Qin |
| author_facet | Jiaxing Tan Nuozhou Liu Peiyan Sun Yi Tang Wei Qin |
| author_sort | Jiaxing Tan |
| collection | DOAJ |
| description | This was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was assessed by dietary inflammatory index (DII) based on 24 h dietary recall. Mortality follow-up information was accessed from NDI, which was then merged with NHANES data following the National Center for Health Statistics (NCHS) protocols. For 15,291 participants from the general population, the average DII was 0.37 ± 1.76 and the prevalence rate of diabetes was 13.26%. DII was positively associated with fasting glucose (β = 0.83, 95% CI: 0.30, 1.36, <i>p</i> = 0.0022), glycohemoglobin (β = 0.02, 95% CI: 0.01, 0.03, <i>p</i> = 0.0009), and the risk of diabetes (OR = 1.05, 95% CI: 1.01, 1.09, <i>p</i> = 0.0139). For 1904 participants with diabetes and a median follow-up of 45 person-months, a total of 178 participants with diabetes died from all causes (mortality rate = 9.34%). People with diabetes who adhered to a proinflammatory diet showed a higher risk of all-cause mortality (HR = 1.71, 95%CI: 1.13, 2.58, <i>p</i> = 0.0108). In summary, DII was positively associated with diabetes prevalence and a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. |
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| issn | 2072-6643 |
| language | English |
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| spelling | doaj.art-d0e0f430dc3744fca9a0785a2c1f3c462023-11-23T12:28:35ZengMDPI AGNutrients2072-66432022-05-011410201110.3390/nu14102011A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes MellitusJiaxing Tan0Nuozhou Liu1Peiyan Sun2Yi Tang3Wei Qin4Division of Nephrology, Department of Medicine, West China Hospital, Sichuan University, Guoxuexiang Street, Chengdu 610041, ChinaWest China School of Medicine, Sichuan University, Chengdu 610041, ChinaWest China School of Medicine, Sichuan University, Chengdu 610041, ChinaDivision of Nephrology, Department of Medicine, West China Hospital, Sichuan University, Guoxuexiang Street, Chengdu 610041, ChinaDivision of Nephrology, Department of Medicine, West China Hospital, Sichuan University, Guoxuexiang Street, Chengdu 610041, ChinaThis was an observational study based on the National Health and Nutrition Examination Survey (NHANES) and National Death Index (NDI) 2009–2014 which aimed to validate whether a proinflammatory diet may increase mortality risk in patients with diabetes mellitus. Dietary inflammatory potential was assessed by dietary inflammatory index (DII) based on 24 h dietary recall. Mortality follow-up information was accessed from NDI, which was then merged with NHANES data following the National Center for Health Statistics (NCHS) protocols. For 15,291 participants from the general population, the average DII was 0.37 ± 1.76 and the prevalence rate of diabetes was 13.26%. DII was positively associated with fasting glucose (β = 0.83, 95% CI: 0.30, 1.36, <i>p</i> = 0.0022), glycohemoglobin (β = 0.02, 95% CI: 0.01, 0.03, <i>p</i> = 0.0009), and the risk of diabetes (OR = 1.05, 95% CI: 1.01, 1.09, <i>p</i> = 0.0139). For 1904 participants with diabetes and a median follow-up of 45 person-months, a total of 178 participants with diabetes died from all causes (mortality rate = 9.34%). People with diabetes who adhered to a proinflammatory diet showed a higher risk of all-cause mortality (HR = 1.71, 95%CI: 1.13, 2.58, <i>p</i> = 0.0108). In summary, DII was positively associated with diabetes prevalence and a proinflammatory diet may increase mortality risk in patients with diabetes mellitus.https://www.mdpi.com/2072-6643/14/10/2011dietary inflammatory indexdiabetes mellitusall-cause mortalityNational Death IndexNHANES |
| spellingShingle | Jiaxing Tan Nuozhou Liu Peiyan Sun Yi Tang Wei Qin A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus Nutrients dietary inflammatory index diabetes mellitus all-cause mortality National Death Index NHANES |
| title | A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus |
| title_full | A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus |
| title_fullStr | A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus |
| title_full_unstemmed | A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus |
| title_short | A Proinflammatory Diet May Increase Mortality Risk in Patients with Diabetes Mellitus |
| title_sort | proinflammatory diet may increase mortality risk in patients with diabetes mellitus |
| topic | dietary inflammatory index diabetes mellitus all-cause mortality National Death Index NHANES |
| url | https://www.mdpi.com/2072-6643/14/10/2011 |
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