High Frequency of Cell-in-Cell Formation in Heterogeneous Human Breast Cancer Tissue in a Patient With Poor Prognosis: A Case Report and Literature Review

High Frequency of Cell-in-Cell Formation in Heterogeneous Human Breast Cancer Tissue in a Patient With Poor Prognosis: A Case Report and Literature Review

Cell cannibalism is a unique pathological phenomenon that has been observed at low frequency in a variety of human tumor samples (<0.5%), including breast cancer. Cannibalistic cells typically form cell-in-cell (CIC) structures characterized by enclosure of one cell or more by another, mediat...

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Bibliographic Details
Main Authors: Banzhan Ruan, Zubiao Niu, Xiaoyi Jiang, Zhuo Li, Yanhong Tai, Hongyan Huang, Qiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
cell-in-cell formation
cell cannibalism
entosis
heterogeneity
breast cancer
poor prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01444/full

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