Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature

The reactivation of human herpesvirus 6 (HHV-6) in patients with AIDS can result in an acute and severe diffuse meningoencephalitis. We describe the epidemiological, clinical and outcome findings of five patients with diagnosis of HIV/AIDS and central nervous system involvement (CNS) due to HHV-6. F...

Full description

Bibliographic Details
Main Authors: Marcelo Corti, Maria Florencia Villafañe, Norberto Trione, Lilia Mamanna, Belén Bouzas
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2011-08-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000400026&lng=en&tlng=en
_version_ 1811243599403155456
author Marcelo Corti
Maria Florencia Villafañe
Norberto Trione
Lilia Mamanna
Belén Bouzas
author_facet Marcelo Corti
Maria Florencia Villafañe
Norberto Trione
Lilia Mamanna
Belén Bouzas
author_sort Marcelo Corti
collection DOAJ
description The reactivation of human herpesvirus 6 (HHV-6) in patients with AIDS can result in an acute and severe diffuse meningoencephalitis. We describe the epidemiological, clinical and outcome findings of five patients with diagnosis of HIV/AIDS and central nervous system involvement (CNS) due to HHV-6. Fever was present in all the patients. Meningeal compromise, seizures and encephalitis were present in some of the patients. Polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) specimens was positive for HHV-6 in all the patients. HHV-6 should be included among opportunistic and emerging pathogens that involve the CNS in patients with AIDS.
first_indexed 2024-04-12T14:10:08Z
format Article
id doaj.art-d0e3a4156b6a4ca4a2bd9e1b1f19f8eb
institution Directory Open Access Journal
issn 1678-9849
language English
last_indexed 2024-04-12T14:10:08Z
publishDate 2011-08-01
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
record_format Article
series Revista da Sociedade Brasileira de Medicina Tropical
spelling doaj.art-d0e3a4156b6a4ca4a2bd9e1b1f19f8eb2022-12-22T03:29:55ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492011-08-0144452252510.1590/S0037-86822011000400026S0037-86822011000400026Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literatureMarcelo Corti0Maria Florencia Villafañe1Norberto Trione2Lilia Mamanna3Belén Bouzas4Hospital de Enfermedades Infecciosas Dr. Francisco Javier MuñizHospital de Enfermedades Infecciosas Dr. Francisco Javier MuñizHospital de Enfermedades Infecciosas Dr. Francisco Javier MuñizHospital de Enfermedades Infecciosas Dr. Francisco Javier MuñizHospital de Enfermedades Infecciosas Dr. Francisco Javier MuñizThe reactivation of human herpesvirus 6 (HHV-6) in patients with AIDS can result in an acute and severe diffuse meningoencephalitis. We describe the epidemiological, clinical and outcome findings of five patients with diagnosis of HIV/AIDS and central nervous system involvement (CNS) due to HHV-6. Fever was present in all the patients. Meningeal compromise, seizures and encephalitis were present in some of the patients. Polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) specimens was positive for HHV-6 in all the patients. HHV-6 should be included among opportunistic and emerging pathogens that involve the CNS in patients with AIDS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000400026&lng=en&tlng=enAIDSHIVMeningoencefaliteMeningiteHHV-6
spellingShingle Marcelo Corti
Maria Florencia Villafañe
Norberto Trione
Lilia Mamanna
Belén Bouzas
Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
Revista da Sociedade Brasileira de Medicina Tropical
AIDS
HIV
Meningoencefalite
Meningite
HHV-6
title Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
title_full Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
title_fullStr Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
title_full_unstemmed Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
title_short Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature
title_sort human herpesvirus 6 report of emerging pathogen in five patients with hiv aids and review of the literature
topic AIDS
HIV
Meningoencefalite
Meningite
HHV-6
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000400026&lng=en&tlng=en
work_keys_str_mv AT marcelocorti humanherpesvirus6reportofemergingpathogeninfivepatientswithhivaidsandreviewoftheliterature
AT mariaflorenciavillafane humanherpesvirus6reportofemergingpathogeninfivepatientswithhivaidsandreviewoftheliterature
AT norbertotrione humanherpesvirus6reportofemergingpathogeninfivepatientswithhivaidsandreviewoftheliterature
AT liliamamanna humanherpesvirus6reportofemergingpathogeninfivepatientswithhivaidsandreviewoftheliterature
AT belenbouzas humanherpesvirus6reportofemergingpathogeninfivepatientswithhivaidsandreviewoftheliterature