Synthesis and Biological Studies on (KLAKLAK)<sub>2</sub>-NH<sub>2</sub> Analog Containing Unnatural Amino Acid β-Ala and Conjugates with Second Pharmacophore

Synthesis and Biological Studies on (KLAKLAK)<sub>2</sub>-NH<sub>2</sub> Analog Containing Unnatural Amino Acid β-Ala and Conjugates with Second Pharmacophore

(1) Background: Peptides are good candidates for anticancer drugs due to their natural existence in the body and lack of secondary effects. (KLAKLAK)<sub>2</sub> is an antimicrobial peptide that also shows good anticancer properties. (2) Methods: The Solid Phase Peptide Synthesis (Fmoc-s...

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Bibliographic Details
Main Authors:	Sirine Jaber, Veronica Nemska, Ivan Iliev, Elena Ivanova, Tsvetelina Foteva, Nelly Georgieva, Ivan Givechev, Emilia Naydenova, Veronika Karadjova, Dancho Danalev
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Molecules
Subjects:	(KLAKLAK)<sub>2</sub> antitumor peptides 1,8-naphthalimide caffeic acid unnatural amino acids
Online Access:	https://www.mdpi.com/1420-3049/26/23/7321

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