Spatial geometric and magnetic resonance signal intensity changes with advancing stages of nucleus pulposus degeneration
Abstract Background With advancing stages of degeneration, denaturation and degradation of proteoglycans in the nucleus pulposus (NP) lead to tissue dehydration and signal intensity loss on T2-weighted MR images. Pfirrmann grading is widely used for grading degeneration of intervertebral discs (IVDs...
Main Authors: | Shu-Hua Yang, Alejandro A. Espinoza Orías, Chien-Chou Pan, Issei Senoo, Gunnar B. J. Andersson, Howard S. An, Nozomu Inoue |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | BMC Musculoskeletal Disorders |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12891-017-1838-0 |
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