The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease
Background There are limited number of studies that investigate clinical variables instead of chronic obstructive lung disease (COPD) management according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classification. The aim of the study was to investigate whether there wa...
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| Format: | Article |
| Language: | English |
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The Korean Academy of Tuberculosis and Respiratory Diseases
2018-10-01
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| Series: | Tuberculosis and Respiratory Diseases |
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| Online Access: | https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0114&code=0003TRD&vmode=FULL |
| _version_ | 1818758119626375168 |
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| author | Ipek Candemir, M.D. Pinar Ergun, M.D. Dicle Kaymaz, M.D. Filiz Tasdemir Nurcan Egesel |
| author_facet | Ipek Candemir, M.D. Pinar Ergun, M.D. Dicle Kaymaz, M.D. Filiz Tasdemir Nurcan Egesel |
| author_sort | Ipek Candemir, M.D. |
| collection | DOAJ |
| description | Background
There are limited number of studies that investigate clinical variables instead of chronic obstructive lung disease (COPD) management according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classification. The aim of the study was to investigate whether there was a difference between GOLD 2017 classification and spirometric stage in clinical variables in patients with COPD. The data of 427 male patients with stable COPD were investigated retrospectively.
Methods
Patients were allocated into combined assessment of GOLD 2017 and spirometric stage. Age, amount of smoking, pulmonary function, modified Medical Research Council (mMRC), incremental shuttle walk test (ISWT), Hospital Anxiety-Depression Scale (HADS), St. George's Respiratory Questionnaire (SGRQ), body mass index (BMI), and fat free mass index (FFMI) were recorded.
Results
Seventy-three (17%) patients were in group A, 103 (24%) constituted group B, 38 (9%) were included in group C, and 213 (50%) comprised group D according to the combined assessment of GOLD 2017. Twenty-three patients (5%) were in stage 1, 95 (22%) were in stage 2, 149 (35%) were in stage 3, and 160 (38%) were in stage 4 according to spirometric stage. According to GOLD 2017, age, amount of smoking, mMRC, BMI, FFMI, SGRQ, HADS, forced vital capacity, forced expiratory volume in 1 second (FEV1), and ISWT were significantly different between groups. Ages, amount of smoking, FFMI, BMI, HADS of group A were different from B and D. Smiliar values of FEV1 were found in A–C and B–D. A and C had smiliar ISWT. According to spirometric stage, BMI, FFMI of stage 4 were statistically different. mMRC, ISWT, and SGRQ of stages 3 and 4 were different from other stages, amongst themselves. FEV1 was correlated with mMRC, SGRQ, anxiety scores, BMI, FFMI, and ISWT.
Conclusion
This study showed that the GOLD ABCD classification might not represent the severity of COPD sufficiently well in terms of lung function or exercise capacity. The combination of both spirometric stage and combined assessment of GOLD 2017 is important, especially for estimating clinical variables. |
| first_indexed | 2024-12-18T06:21:46Z |
| format | Article |
| id | doaj.art-d0ebf3dcbabb4136b6c3af6226b7d321 |
| institution | Directory Open Access Journal |
| issn | 1738-3536 2005-6184 |
| language | English |
| last_indexed | 2024-12-18T06:21:46Z |
| publishDate | 2018-10-01 |
| publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
| record_format | Article |
| series | Tuberculosis and Respiratory Diseases |
| spelling | doaj.art-d0ebf3dcbabb4136b6c3af6226b7d3212022-12-21T21:18:09ZengThe Korean Academy of Tuberculosis and Respiratory DiseasesTuberculosis and Respiratory Diseases1738-35362005-61842018-10-01814281288The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary DiseaseIpek Candemir, M.D.0Pinar Ergun, M.D.1Dicle Kaymaz, M.D.2Filiz Tasdemir3Nurcan Egesel4Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmoner Rehabilitation and Home Care Center, Ankara, Turkey.Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmoner Rehabilitation and Home Care Center, Ankara, Turkey.Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmoner Rehabilitation and Home Care Center, Ankara, Turkey.Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmoner Rehabilitation and Home Care Center, Ankara, Turkey.Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmoner Rehabilitation and Home Care Center, Ankara, Turkey.Background There are limited number of studies that investigate clinical variables instead of chronic obstructive lung disease (COPD) management according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classification. The aim of the study was to investigate whether there was a difference between GOLD 2017 classification and spirometric stage in clinical variables in patients with COPD. The data of 427 male patients with stable COPD were investigated retrospectively. Methods Patients were allocated into combined assessment of GOLD 2017 and spirometric stage. Age, amount of smoking, pulmonary function, modified Medical Research Council (mMRC), incremental shuttle walk test (ISWT), Hospital Anxiety-Depression Scale (HADS), St. George's Respiratory Questionnaire (SGRQ), body mass index (BMI), and fat free mass index (FFMI) were recorded. Results Seventy-three (17%) patients were in group A, 103 (24%) constituted group B, 38 (9%) were included in group C, and 213 (50%) comprised group D according to the combined assessment of GOLD 2017. Twenty-three patients (5%) were in stage 1, 95 (22%) were in stage 2, 149 (35%) were in stage 3, and 160 (38%) were in stage 4 according to spirometric stage. According to GOLD 2017, age, amount of smoking, mMRC, BMI, FFMI, SGRQ, HADS, forced vital capacity, forced expiratory volume in 1 second (FEV1), and ISWT were significantly different between groups. Ages, amount of smoking, FFMI, BMI, HADS of group A were different from B and D. Smiliar values of FEV1 were found in A–C and B–D. A and C had smiliar ISWT. According to spirometric stage, BMI, FFMI of stage 4 were statistically different. mMRC, ISWT, and SGRQ of stages 3 and 4 were different from other stages, amongst themselves. FEV1 was correlated with mMRC, SGRQ, anxiety scores, BMI, FFMI, and ISWT. Conclusion This study showed that the GOLD ABCD classification might not represent the severity of COPD sufficiently well in terms of lung function or exercise capacity. The combination of both spirometric stage and combined assessment of GOLD 2017 is important, especially for estimating clinical variables.https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0114&code=0003TRD&vmode=FULLpulmonary diseasechronic obstructivequality of lifedyspnea |
| spellingShingle | Ipek Candemir, M.D. Pinar Ergun, M.D. Dicle Kaymaz, M.D. Filiz Tasdemir Nurcan Egesel The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease Tuberculosis and Respiratory Diseases pulmonary disease chronic obstructive quality of life dyspnea |
| title | The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease |
| title_full | The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease |
| title_fullStr | The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease |
| title_full_unstemmed | The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease |
| title_short | The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease |
| title_sort | comparison of clinical variables in two classifications gold 2017 combined assessment and spirometric stage of chronic obstructive pulmonary disease |
| topic | pulmonary disease chronic obstructive quality of life dyspnea |
| url | https://e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0114&code=0003TRD&vmode=FULL |
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