Depression and Cognitive Performances in Patients with Multiple Sclerosis
Background: Cognitive deficits are common complaints voiced by patients with multiple sclerosis (MS). Several studies have confirmed these deficits. In the other hand, depression has considerable evidence in these patients; whereas, depression can affect the cognitive performances; it is possible th...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2015-06-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/4591 |
| _version_ | 1797720222845632512 |
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| author | Mahgol Tavakoli Maryam Sharifi Vahid Shaygannejad |
| author_facet | Mahgol Tavakoli Maryam Sharifi Vahid Shaygannejad |
| author_sort | Mahgol Tavakoli |
| collection | DOAJ |
| description | Background: Cognitive deficits are common complaints voiced by patients with multiple sclerosis (MS). Several studies have confirmed these deficits. In the other hand, depression has considerable evidence in these patients; whereas, depression can affect the cognitive performances; it is possible that some of these confirmed cognitive deficits had been caused by depression. This study investigated and compared the cognitive performances of depressed and non-depressed patients with multiple sclerosis and healthy controls.
Methods: In this causal-comparative research, 52 patients with multiple sclerosis (26 depressed and 26 non-depressed patients) from Kashani hospital in Isfahan, Iran, and 26 healthy controls were selected. They were assessed through the Beck Depression Inventory (BDI-II), Color Trail Test (CTT), verbal memory test and visual memory test. The data was analyzed using covariance method.
Findings: There were significant differences in attention, immediate and delayed (recall) verbal memory performance between the depressed patients with multiple sclerosis and the two other groups (P = 0.002). In additon, there were significant differences in delayed (recall and recognition) visual memory performance between healthy group and the two other groups (P = 0.020). But, there were no significant differences, in immediate visual and delayed (recognition) verbal memory performances, between the three groups.
Conclusion: The cognitive performance of the patients with multiple sclerosis not only is affected by neurologic injuries but also it is affected by depression. Depression can cause or intensify the cognitive deficits of the patients with multiple sclerosis. |
| first_indexed | 2024-03-12T09:16:22Z |
| format | Article |
| id | doaj.art-d0ec8530457d441186f353fef737772c |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:16:22Z |
| publishDate | 2015-06-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-d0ec8530457d441186f353fef737772c2023-09-02T14:49:01ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2015-06-01333326046141863Depression and Cognitive Performances in Patients with Multiple SclerosisMahgol Tavakoli0Maryam Sharifi1Vahid Shaygannejad2Assistant Professor, Department of Psychology, School of Psychology and Educational Science, University of Isfahan, Isfahan, IranPhD Student, Department of Psychology, School of Psychology and Educational Science, University of Isfahan, Isfahan, IranAssociate Professor, Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranBackground: Cognitive deficits are common complaints voiced by patients with multiple sclerosis (MS). Several studies have confirmed these deficits. In the other hand, depression has considerable evidence in these patients; whereas, depression can affect the cognitive performances; it is possible that some of these confirmed cognitive deficits had been caused by depression. This study investigated and compared the cognitive performances of depressed and non-depressed patients with multiple sclerosis and healthy controls. Methods: In this causal-comparative research, 52 patients with multiple sclerosis (26 depressed and 26 non-depressed patients) from Kashani hospital in Isfahan, Iran, and 26 healthy controls were selected. They were assessed through the Beck Depression Inventory (BDI-II), Color Trail Test (CTT), verbal memory test and visual memory test. The data was analyzed using covariance method. Findings: There were significant differences in attention, immediate and delayed (recall) verbal memory performance between the depressed patients with multiple sclerosis and the two other groups (P = 0.002). In additon, there were significant differences in delayed (recall and recognition) visual memory performance between healthy group and the two other groups (P = 0.020). But, there were no significant differences, in immediate visual and delayed (recognition) verbal memory performances, between the three groups. Conclusion: The cognitive performance of the patients with multiple sclerosis not only is affected by neurologic injuries but also it is affected by depression. Depression can cause or intensify the cognitive deficits of the patients with multiple sclerosis.http://jims.mui.ac.ir/index.php/jims/article/view/4591Multiple sclerosisDepressionAttentionVisual MemoryVerbal memory |
| spellingShingle | Mahgol Tavakoli Maryam Sharifi Vahid Shaygannejad Depression and Cognitive Performances in Patients with Multiple Sclerosis مجله دانشکده پزشکی اصفهان Multiple sclerosis Depression Attention Visual Memory Verbal memory |
| title | Depression and Cognitive Performances in Patients with Multiple Sclerosis |
| title_full | Depression and Cognitive Performances in Patients with Multiple Sclerosis |
| title_fullStr | Depression and Cognitive Performances in Patients with Multiple Sclerosis |
| title_full_unstemmed | Depression and Cognitive Performances in Patients with Multiple Sclerosis |
| title_short | Depression and Cognitive Performances in Patients with Multiple Sclerosis |
| title_sort | depression and cognitive performances in patients with multiple sclerosis |
| topic | Multiple sclerosis Depression Attention Visual Memory Verbal memory |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/4591 |
| work_keys_str_mv | AT mahgoltavakoli depressionandcognitiveperformancesinpatientswithmultiplesclerosis AT maryamsharifi depressionandcognitiveperformancesinpatientswithmultiplesclerosis AT vahidshaygannejad depressionandcognitiveperformancesinpatientswithmultiplesclerosis |